Traumatic spinal cord injury (SCI) is a devastating neurological condition that results in a
loss of motor and sensory function. Although extensive research to develop treatments for …

Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

Spinal cord injury (SCI) is an overwhelming and incurable disabling event accompanied by
complicated inflammation-related pathological processes, such as excessive reactive …

Virtually all phases of spinal cord injury pathogenesis, including inflammation, cell
proliferation and differentiation, as well as tissue remodeling, are mediated in part by …

In spinal cord injury (SCI), the initial damage leads to a rapidly escalating cascade of
degenerative events, known as secondary injury. Loss of mitochondrial homeostasis after …

Background Minocycline is a clinically available synthetic tetracycline derivative with anti-
inflammatory and antibiotic properties. The majority of studies show that minocycline can …

Traumatic spinal cord injury (SCI) is a devastating condition that significantly impacts motor,
sensory and autonomic function in patients. Despite advances in therapeutic approaches …

Spinal cord injury (SCI) disturbs the autonomic nervous system and induces dysfunction in
multiple organs/tissues, such as the gastrointestinal (GI) system. The neuroprotective effects …

After spinal cord injury, there is an extensive infiltration of immune cells, which exacerbates
the injury and leads to further neural degeneration. Therefore, a major aim of current …

NADPH oxidase (NOX2) is an enzyme that induces reactive oxygen species (ROS) and
serves as a switch between the pro-inflammatory and neurorestorative microglial …