Subthalamic deep brain stimulation (DBS) for Parkinson disease (PD) currently requires
laborious open-loop programming, which can mitigate the benefits of this treatment …

The field of stereotactic neurosurgery developed more than 70 years ago to address a
therapy gap for patients with severe psychiatric disorders. In the decades since, it has …

Multiple surgical targets for treating obsessive-compulsive disorder with deep brain
stimulation (DBS) have been proposed. However, different targets may modulate the same …

Background Deep brain stimulation (DBS) has been proposed as an alternative to ablative
neurosurgery for severe treatment-resistant Obsessive-Compulsive Disorder (OCD) …

Background Severe, refractory obsessive–compulsive disorder (OCD) is a disabling
condition. Stimulation of the subthalamic nucleus, a procedure that is already validated for …

Deep brain stimulation at high frequency was first used in 1997 to replace thalamotomy in
treating the characteristic tremor of Parkinson's disease, and has subsequently been applied …

Highlights•Involvement of corticostriatal circuits in OCD is receiving strong new experimental
support.•This evidence is concordant with clinical evidence based on OCD patient …

Deep brain stimulation (DBS) of the anterior limb of the internal capsule has been shown to
be beneficial in the short term for obsessive–compulsive disorder (OCD) patients who …

Objective: To prospectively evaluate the impact of subthalamic nucleus (STN) stimulation on
social adjustment in patients with Parkinson disease (PD). Methods: Before and 18 to 24 …

OBJECTIVE: Because of the irreversibility of lesioning procedures and their possible side
effects, we studied the efficacy of replacing bilateral anterior capsulotomy with chronic …