Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

Background Fungal infections of the central nervous system (FIs-CNS) have become
significantly more common over the past 2 decades. Invasion of the CNS largely depends on …

Fungal infections are a global concern and the evolution of intrinsic resistance to current
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …

Cryptococcosis is a life-threatening fungal infection caused by the encapsulated yeasts
Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as …

Racial and ethnic identities, largely understood as social rather than biologic constructs,
may impact risk for acquiring infectious diseases, including fungal infections. Risk factors …

These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the diagnosis, prevention, and management of …

Fungal infections of the CNS are challenging to treat and their optimal management requires
knowledge of their epidemiology, host characteristics, diagnostic criteria, and therapeutic …

Fungal cells change shape in response to environmental stimuli, and these morphogenic
transitions drive pathogenesis and niche adaptation. For example, dimorphic fungi switch …

Cryptococcosis is a potentially lethal disease that is primarily caused by the fungus
Cryptococcus neoformans, treatment options for cryptococcosis are limited. Here, we show …

Infectious meningitis can be caused by viral, bacterial or fungal pathogens. Despite widely
available treatments, many types of infectious meningitis are still associated with significant …