The physics of proton therapy

WD Newhauser, R Zhang - Physics in Medicine & Biology, 2015 - iopscience.iop.org
The physics of proton therapy has advanced considerably since it was proposed in 1946.
Today analytical equations and numerical simulation methods are available to predict and …

Nuclear physics in particle therapy: a review

M Durante, H Paganetti - Reports on Progress in Physics, 2016 - iopscience.iop.org
Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

AAPM TG 158: measurement and calculation of doses outside the treated volume from external‐beam radiation therapy

SF Kry, B Bednarz, RM Howell, L Dauer… - Medical …, 2017 - Wiley Online Library
The introduction of advanced techniques and technology in radiotherapy has greatly
improved our ability to deliver highly conformal tumor doses while minimizing the dose to …

A review of dosimetry studies on external-beam radiation treatment with respect to second cancer induction

XG Xu, B Bednarz, H Paganetti - Physics in Medicine & Biology, 2008 - iopscience.iop.org
It has been long known that patients treated with ionizing radiation carry a risk of developing
a second cancer in their lifetimes. Factors contributing to the recently renewed concern …

Proton vs carbon ion beams in the definitive radiation treatment of cancer patients

H Suit, T DeLaney, S Goldberg, H Paganetti… - Radiotherapy and …, 2010 - Elsevier
BACKGROUND AND PURPOSE: Relative to X-ray beams, proton [1H] and carbon ion [12C]
beams provide superior distributions due primarily to their finite range. The principal …

Management of radiotherapy patients with implanted cardiac pacemakers and defibrillators: A Report of the AAPM TG‐203

M Miften, D Mihailidis, SF Kry, C Reft… - Medical …, 2019 - Wiley Online Library
Managing radiotherapy patients with implanted cardiac devices (implantable cardiac
pacemakers and implantable cardioverter‐defibrillators) has been a great practical and …

Secondary neutrons in clinical proton radiotherapy: a charged issue

DJ Brenner, EJ Hall - Radiotherapy and Oncology, 2008 - Elsevier
Hospital-based proton facilities may represent a major advance in radiation therapy, in part
because of excellent dose distributions around the tumor, and in part because of the …

A review of radiotherapy-induced late effects research after advanced technology treatments

WD Newhauser, AB De Gonzalez, R Schulte… - Frontiers in …, 2016 - frontiersin.org
The number of incident cancers and long-term cancer survivors is expected to increase
substantially for at least a decade. Advanced technology radiotherapies, eg, using beams of …

Biological considerations when comparing proton therapy with photon therapy

H Paganetti, P Van Luijk - Seminars in radiation oncology, 2013 - Elsevier
Owing to the limited availability of data on the outcome of proton therapy, treatments are
generally optimized based on broadly available data on photon-based treatments. However …

Clinical commissioning of intensity‐modulated proton therapy systems: report of AAPM Task Group 185

JB Farr, MF Moyers, CE Allgower, M Bues… - Medical …, 2021 - Wiley Online Library
Proton therapy is an expanding radiotherapy modality in the United States and worldwide.
With the number of proton therapy centers treating patients increasing, so does the need for …