Muc4/MUC4 functions and regulation in cancer
KL Carraway, G Theodoropoulos, GA Kozloski… - Future …, 2009 - Future Medicine
The membrane mucin MUC4 (human) is abundantly expressed in many epithelia, where it is
proposed to play a protective role, and is overexpressed in some epithelial tumors. Studies …
proposed to play a protective role, and is overexpressed in some epithelial tumors. Studies …
Regulatory pathways in lacrimal gland epithelium
Tears are a complex fluid that continuously cover the exposed surface of the eye, namely the
cornea and conjunctiva. Tears are secreted in response to the multitude of environmental …
cornea and conjunctiva. Tears are secreted in response to the multitude of environmental …
Rat Muc4 (sialomucin complex) reduces binding of anti‐ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance
SA Price‐Schiavi, S Jepson, P Li… - … journal of cancer, 2002 - Wiley Online Library
Muc4 (also called sialomucin complex), the rat homolog of human MUC4, is a heterodimeric
glycoprotein complex that consists of a peripheral O‐glycosylated mucin subunit, ASGP‐1 …
glycoprotein complex that consists of a peripheral O‐glycosylated mucin subunit, ASGP‐1 …
[HTML][HTML] Detection of sialomucin complex (MUC4) in human ocular surface epithelium and tear fluid
SC Pflugfelder, Z Liu, D Monroy, DQ Li… - … & visual science, 2000 - arvojournals.org
purpose. To evaluate human ocular surface epithelium and tear fluid for the presence of
sialomucin complex (MUC4), a high-molecular-weight heterodimeric glycoprotein composed …
sialomucin complex (MUC4), a high-molecular-weight heterodimeric glycoprotein composed …
[HTML][HTML] Reversible disruption of cell-matrix and cell-cell interactions by overexpression of sialomucin complex
M Komatsu, CAC Carraway, NL Fregien… - Journal of Biological …, 1997 - ASBMB
Sialomucin complex (SMC) is a large, heterodimeric glycoprotein complex composed of
mucin (ASGP-1) and transmembrane (ASGP-2) subunits and expressed abundantly on the …
mucin (ASGP-1) and transmembrane (ASGP-2) subunits and expressed abundantly on the …
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27kip, but does not activate …
Abstract Muc4/sialomucin complex (SMC) is a multifunctional glycoprotein complex which
can repress apoptosis in transfected tumor cells. Its transmembrane subunit acts as an …
can repress apoptosis in transfected tumor cells. Its transmembrane subunit acts as an …
Muc4/sialomucin complex, the intramembrane Er6B2 ligand, in cancer and epithelia: to protect and to survive
The membrane mucin Muc4, also called sialomucin complex (SMC), is a heterodimeric
complex of two subunits, ASGP-1 and ASGP-2, derived from a single gene. It is produced by …
complex of two subunits, ASGP-1 and ASGP-2, derived from a single gene. It is produced by …
[HTML][HTML] Post-translational protein modification and expression of ankyrin-binding site (s) in GP85 (Pgp-1/CD44) and its biosynthetic precursors during T-lymphoma …
VB Lokeshwar, LY Bourguignon - Journal of Biological Chemistry, 1991 - Elsevier
In this study, we have investigated the biosynthesis and processing of GP85 (Pgp-1/CD44),
a lymphoma transmembrane glycoprotein known to contain ankyrin-binding site (s). Using a …
a lymphoma transmembrane glycoprotein known to contain ankyrin-binding site (s). Using a …
[HTML][HTML] Visual field losses in subjects with migraine headaches
AM McKendrick, AJ Vingrys… - … & visual science, 2000 - iovs.arvojournals.org
purpose. To characterize the visual fields of subjects with migraine headaches using static
and temporal modulation perimetry. methods. Sixteen subjects with migraines (15 with aura …
and temporal modulation perimetry. methods. Sixteen subjects with migraines (15 with aura …
[HTML][HTML] Differential regulation of membrane-associated mucins in the human ocular surface epithelium
Y Hori, S Spurr-Michaud, CL Russo… - … & visual science, 2004 - iovs.arvojournals.org
purpose. Membrane-associated mucins present in the apical cells of the ocular surface
epithelium (MUC1,-4, and-16) are believed to contribute to the maintenance of a hydrated …
epithelium (MUC1,-4, and-16) are believed to contribute to the maintenance of a hydrated …