Stimuli-responsive polymer-based nanosystems for cancer theranostics
D Wei, Y Sun, H Zhu, Q Fu - ACS nano, 2023 - ACS Publications
Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …
Recent advances in hyaluronic acid-based nanomedicines: Preparation and application in cancer therapy
Rapid development of stimuli-responsive drug delivery systems (DDSs) for tumor therapy
has raised increasing interest in recent decades, and many nanomedicines are prepared to …
has raised increasing interest in recent decades, and many nanomedicines are prepared to …
ROS-responsive camptothecin-linked thioketal drug delivery system based on ring-closing polymerization
This study develops a drug delivery system that is ROS-responsive and can be triggered by
endogenous ROS. A polyethylene glycol (PEG) tail end is attached to a ring-closing polymer …
endogenous ROS. A polyethylene glycol (PEG) tail end is attached to a ring-closing polymer …
Accommodation of ring C expanded deoxyvasicinone in the HDAC inhibitory pharmacophore culminates into a tractable anti-lung cancer agent and pH-responsive …
A fragment recruitment process was conducted to pinpoint a suitable fragment for installation
in the HDAC inhibitory template to furnish agents endowed with the potential to treat lung …
in the HDAC inhibitory template to furnish agents endowed with the potential to treat lung …
Polysaccharides for Medical Technology: Properties and Applications
P Sukhavattanakul, P Pisitsak… - Macromolecular …, 2023 - Wiley Online Library
Over the past decade, the use of polysaccharides has gained tremendous attention in the
field of medical technology. They have been applied in various sectors such as tissue …
field of medical technology. They have been applied in various sectors such as tissue …
Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation
Careful recruitment of the components of the HDAC inhibitory template culminated in
veliparib-based anilide 8 that elicited remarkable cell growth inhibitory effects against HL-60 …
veliparib-based anilide 8 that elicited remarkable cell growth inhibitory effects against HL-60 …
Fungal Keratitis Treatment Using Drug-Loaded Hyaluronic Acid Microgels
RS Ayyala, S S. Suner, VR Bhethanabotla… - ACS Applied Bio …, 2022 - ACS Publications
Antifungal drug-loaded hyaluronic acid (HA) microgels using conjugation and encapsulation
drug-loading techniques were utilized in the treatment of fungal keratitis. Natamycin (NAT) …
drug-loading techniques were utilized in the treatment of fungal keratitis. Natamycin (NAT) …
Polynorbornene-derived block copolymer micelles via ring‐opening metathesis polymerization with capacity of hydrogen sulfide generation
Abstract Hydrogen sulfide (H 2 S), a gasotransmitter, has recently attracted significant
attention for its therapeutic properties. In order to achieve controlled H 2 S release, polymer …
attention for its therapeutic properties. In order to achieve controlled H 2 S release, polymer …
A hyaluronic-based prodrug with aggregation-induced emission for drug delivery and cellular imaging
HP Pham, VR Neralla - Journal of Macromolecular Science, Part A, 2023 - Taylor & Francis
A novel drug molecule (R6) is conjugated to hyaluronic acid (HA) to form a pH-responsive
prodrug with aggregation-induced emission (AIE) property. Owing to its amphiphilic nature …
prodrug with aggregation-induced emission (AIE) property. Owing to its amphiphilic nature …