Candida albicans, along with other closely related Candida species, are the primary
causative agents of vulvovaginal candidiasis (VVC)—a multifactorial infectious disease of …

Highlights•Candidalysin is the first peptide toxin identified in any human fungal pathogen.•
Candidalysin is critical for Candida albicans mucosal and systemic infections.•Candidalysin …

Clearance of invading microbes requires phagocytes of the innate immune system.
However, successful pathogens have evolved sophisticated strategies to evade immune …

One of the most important questions in microbiology nowadays, is how apparently harmless,
commensal yeasts like Candida spp. can cause a rising number of infections. The …

Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …

Candida albicans infections range from superficial to systemic and are one of the leading
causes of fungus-associated nosocomial infections. The innate immune responses during …

The human pathogenic fungus Candida albicans is a frequent cause of mucosal infections.
Although the ability to transition from the yeast to the hypha morphology is essential for …

Life-threatening systemic infections often occur due to the translocation of pathogens across
the gut barrier and into the bloodstream. While the microbial and host mechanisms …

Denture-related Candida stomatitis, which has been described clinically in the literature, is
either localized or generalized inflammation of the oral mucosa in connection with a …

Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida
albicans, results in significant quality-of-life issues for women worldwide. Candidalysin, a …