Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

Neural respiratory drive, ie, the activity of respiratory centres controlling breathing, is an
overlooked physiologic variable which affects the pathophysiology and the clinical outcome …

Mechanical ventilation can cause acute diaphragm atrophy and injury, and this is associated
with poor clinical outcomes. Although the importance and impact of lung-protective …

Respiratory drive, the intensity of the respiratory center's output, determines the effort
exerted in each breath. The increasing awareness of the adverse effects of both strong and …

Proportional modes of ventilation assist the patient by adapting to his/her effort, which
contrasts with all other modes. The two proportional modes are referred to as neurally …

Background During control mechanical ventilation (CMV), the driving pressure of the
respiratory system (Δ P rs) serves as a surrogate of transpulmonary driving pressure (Δ P …

NAVA and PAV+ for lung and diaphragm protection : Current Opinion in Critical Care NAVA
and PAV+ for lung and diaphragm protection : Current Opinion in Critical Care Log in or …

Background The driving pressure of the respiratory system is a valuable indicator of global
lung stress during passive mechanical ventilation. Monitoring lung stress in assisted …

Introduction: To adhere to the Hippocratic Oath, to 'first, do no harm', we need to make every
effort to minimize the adverse effects of mechanical ventilation. Our understanding of the …

Introduction The driving pressure (Δ P) has an independent association with outcome in
patients with acute respiratory distress syndrome (ARDS). INTELLiVENT-Adaptive Support …