The clinical demand for scaffolds and the diversity of available polymers provide freedom in
the fabrication of scaffolds to achieve successful progress in bone tissue engineering (BTE) …

Runx2 is a master transcription factor for osteogenesis. The most important phenomenon
that makes this protein a master regulator for osteogenesis is its structural integrity. In …

Bone tissue regeneration is augmented by biocompatible nanofiber scaffolds, that supports
reliable and enhanced bone formation. Zinc is an essential mineral that is vital for routine …

Abstract Calcium (Ca) and silica (Si) ions have attracted intense interest in biomedical
applications. The two ions are directly involved in many biological processes; for instance …

The efficient and safe delivery of therapeutic drugs, proteins, and nucleic acids are essential
for meaningful therapeutic benefits. The field of nanomedicine shows promising implications …

Immune reactions are a key factor in determining the destiny of bone substitute materials
after implantation. Macrophages, the most vital factor in the immune response affecting …

Critical-sized bone defects are augmented with cell free and cell loaded constructs to bridge
bone defects. Improving the properties of three-dimensional scaffolds with multiple polymers …

Bone is a self‐engineered structural component of the human body with multifaceted
mechanical strength, which provides indomitable support to the effective functioning of the …

During the last few decades, gold nanoparticles (AuNP's) have gained considerable
attention in nanomedicine and expanded its application in clinical diagnosis and as …

Angiogenesis is considered an important issue in the development of biomaterials for the
successful regeneration of tissues including bone. While growth factors are commonly used …