The field of epitranscriptomics examines the recently deciphered form of gene expression
regulation that is mediated by type-and site-specific RNA modifications. Similarly to the role …

The multiple roles played by RNA binding proteins in neurodegeneration have become
apparent following the discovery of TAR DNA binding protein 43 kDa (TDP‐43) and fused in …

Many proteins regulate the expression of genes by binding to specific regions encoded in
the genome 1. Here we introduce a new data set of RNA elements in the human genome …

As RNA-binding proteins (RBPs) play essential roles in cellular physiology by interacting
with target RNA molecules, binding site identification by UV crosslinking and …

RNA binding proteins are critical to the maintenance of the transcriptome via controlled
regulation of RNA processing and transport. Alterations of these proteins impact multiple …

Through the generation of humanized FUS mice expressing full-length human FUS, we
identify that when expressed at near endogenous murine FUS levels, both wild-type and …

Protein–RNA interactions regulate RNA fate and function, and defects can lead to various
disorders. Such interactions have mainly been studied by nucleoside-based UV crosslinking …

Mutations in genes that encode RNA-binding proteins (RBPs) have emerged as critical
determinants of neurological diseases, especially motor neuron disorders such as …

Alternative precursor-mRNA splicing is a key mechanism for regulating gene expression in
mammals and is controlled by specialized RNA-binding proteins. The misregulation of …

RNA-binding proteins (RBPs) maintain RNA metabolism homeostasis in the cell by
regulating temporal, spatial, and functional dynamics of RNAs. RBPs achieve RNA binding …