The acetylation of histone and non-histone proteins has been implicated in several disease
states. Modulation of such epigenetic modifications has therefore made histone …

In this review, we cover transcription regulation of human immunodeficiency virus type 1
(HIV-1) gene expression, focusing on the invaluable contributions, made by HIV research …

To evade host immune defences, human immunodeficiency viruses 1 and 2 (HIV-1 and HIV-
2) have evolved auxiliary proteins that target cell restriction factors. Viral protein X (Vpx) from …

Emerging evidence indicates that HIV-1 hijacks host DNA damage repair (DDR) pathways to
facilitate multiple facets of virus replication. Canonically, HIV-1 engages proviral DDR …

Porcine epidemic diarrhea virus (PEDV) is an enteric coronavirus causing acute intestinal
infection in pigs, with high mortality often seen in neonatal pigs. The newborns rely on innate …

Background HIV-infected cell lines are widely used to study latent HIV infection, which is
considered the main barrier to HIV cure. We hypothesized that these cell lines differ from …

Abstract Purpose of Review The purpose of this review is to examine the evidence
describing adipose tissue as a reservoir for HIV-1 and how this often expansive anatomic …

Vpr is a lentiviral accessory protein that is expressed late during the infection cycle and is
packaged in significant quantities into virus particles through a specific interaction with the …

Lentiviruses, including HIV-1, possess the ability to enter the nucleus through nuclear pore
complexes and can infect interphase cells, including those actively replicating chromosomal …

Mammals have evolved many antiviral factors impacting different steps of the viral life cycle.
Associated with chromatin-modifying enzymes, the cellular cofactor CTIP2 contributes to HIV …