Overview of microRNA biogenesis, mechanisms of actions, and circulation
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
Role of circular RNAs in brain development and CNS diseases
In mammals, many classes of noncoding RNAs (ncRNAs) are expressed at a much higher
level in the brain than in other organs. Recent studies have identified a new class of ncRNAs …
level in the brain than in other organs. Recent studies have identified a new class of ncRNAs …
microRNA-382 as a tumor suppressor? Roles in tumorigenesis and clinical significance
MicroRNAs (miRNAs) are small single-stranded RNAs belonging to a class of non-coding
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …
The role of microRNAs in inflammation
K Das, LVM Rao - International Journal of Molecular Sciences, 2022 - mdpi.com
Inflammation is a biological response of the immune system to various insults, such as
pathogens, toxic compounds, damaged cells, and radiation. The complex network of pro …
pathogens, toxic compounds, damaged cells, and radiation. The complex network of pro …
Endogenous miRNA sponges
MicroRNAs (miRNAs) are a class of noncoding RNAs of 17–22 nucleotides in length with a
critical function in posttranscriptional gene regulation. These master regulators are …
critical function in posttranscriptional gene regulation. These master regulators are …
Human circulating miRNAs real-time qRT-PCR-based analysis: an overview of endogenous reference genes used for data normalization
miRNAs are small non-coding RNAs of about 18–25 nucleotides that negatively regulate
gene expression at the post-transcriptional level. It was reported that a deregulation of their …
gene expression at the post-transcriptional level. It was reported that a deregulation of their …
CDR1as regulates α-synuclein-mediated ischemic brain damage by controlling miR-7 availability
SL Mehta, AK Chokkalla, S Bathula, V Arruri… - … Therapy-Nucleic Acids, 2023 - cell.com
Transient focal ischemia decreased microRNA-7 (miR-7) levels, leading to derepression of
its major target α-synuclein (α-Syn) that promotes secondary brain damage. Circular RNA …
its major target α-synuclein (α-Syn) that promotes secondary brain damage. Circular RNA …
[HTML][HTML] MicroRNA-486-5p and microRNA-486-3p: Multifaceted pleiotropic mediators in oncological and non-oncological conditions
AM ElKhouly, RA Youness, MZ Gad - Non-coding RNA research, 2020 - Elsevier
Despite historically known as “junk” DNA, nowadays non-coding RNA transcripts (ncRNAs)
are considered as fundamental players in various physiological and pathological conditions …
are considered as fundamental players in various physiological and pathological conditions …
Competing endogenous RNA (ceRNA) networks in Parkinson's disease: A systematic review
MR Asadi, S Abed, G Kouchakali, F Fattahi… - Frontiers in Cellular …, 2023 - frontiersin.org
Parkinson's disease (PD) is a distinctive clinical syndrome with several causes and clinical
manifestations. Aside from an infectious cause, PD is a rapidly developing neurological …
manifestations. Aside from an infectious cause, PD is a rapidly developing neurological …
The role of microRNAs in epithelial ovarian cancer metastasis
Epithelial ovarian cancer (EOC) is the deadliest gynecological cancer, and the major cause
of death is mainly attributed to metastasis. MicroRNAs (miRNAs) are a group of small non …
of death is mainly attributed to metastasis. MicroRNAs (miRNAs) are a group of small non …