Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …

When Szent-Györgyi called water the “matrix of life”, 1 he was echoing an old sentiment.
Paracelsus in the 16th century said that “water was the matrix of the world and of all its …

Alkali (Li+, Na+, K+, Rb+, and Cs+) and halide (F−, Cl−, Br−, and I−) ions play an important
role in many biological phenomena, roles that range from stabilization of biomolecular …

We have examined some subtle parameter modifications to the Cornell et al. force field,
which has proven quite successful in reproducing nucleic acid properties, but whose C2 …

The accurate simulation of DNA and RNA has been a goal of theoretical biophysicists for a
number of years. That is, given a high-resolution experimental structure, or perhaps a …

The quality of biomolecular dynamics simulations relies critically on the force field that is
used to describe the interactions between particles in the system. Force fields, which are …

The systematic study of interactions between metal ions and nucleobases, the constituents
of nucleic acids, as well as nucleic acids in general started some 50 years ago, around …

We describe a very accurate addition (called structure X here) to the B-DNA dodecamer
family of X-ray structures. Our results confirm the observation of Drew and Dickerson [(1981) …

In the last five years we have witnessed a significant increase in the number publications
describing accurate and reliable all‐atom molecular dynamics simulations of nucleic acids …

Room-temperature ionic liquids (RTILs) have generated tremendous interest as nonvolatile
media that provide favorable environments for a wide range of chemical reactions.[1] A …