Exploring the epigenetic drug discovery landscape
V Prachayasittikul, P Prathipati, R Pratiwi… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Epigenetic modification has been implicated in a wide range of diseases and
the ability to modulate such systems is a lucrative therapeutic strategy in drug discovery …
the ability to modulate such systems is a lucrative therapeutic strategy in drug discovery …
Protective actions of vitamin D, anandamide and melatonin during vascular inflammation: Epigenetic mechanisms involved
Vascular inflammation is one of the main activating stimuli of cardiovascular disease and its
uncontrolled development may worsen the progression and prognosis of these pathologies …
uncontrolled development may worsen the progression and prognosis of these pathologies …
Targeting Epigenetics in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a fatal and enigmatic disease of the pulmonary
circulatory system for which there is currently no cure. The intricate pathogenesis of PAH …
circulatory system for which there is currently no cure. The intricate pathogenesis of PAH …
Histone deacetylase inhibitors providing an epigenetic treatment in cancer
T Cinek, N Karalı - Istanbul Journal of Pharmacy, 2021 - dergipark.org.tr
Cancer is among the leading causes of death worldwide and is therefore one of the
diseases in which there have been major medical advances and which is the focus of …
diseases in which there have been major medical advances and which is the focus of …
Characterization of silibinin as a novel epigenetic modulator in prostate carcinoma
A Klavaris - repo.lib.duth.gr
Prostate cancer (PCa) is a multi-factorial disease associated with both genetic and
epigenetic alterations. Especially, epigenetic regulation of PCa involves multiple …
epigenetic alterations. Especially, epigenetic regulation of PCa involves multiple …
[图书][B] Epigenomic profiling of primary hepatocellular carcinoma reveals super-enhancer-associated chromatin regulator network
L Xu - 2019 - search.proquest.com
Epigenomic Profiling of Primary Hepatocellular Carcinoma Reveals Super-enhancer-associated
Chromatin Regulator Network XU, Liang Page 1 Epigenomic Profiling of Primary …
Chromatin Regulator Network XU, Liang Page 1 Epigenomic Profiling of Primary …
From bench to bedside, via desktop. Recent advances in the application of cutting-edge in silico tools in the research of drugs targeting bromodomain modules
V Myrianthopoulos, E Mikros - Biochemical Pharmacology, 2019 - Elsevier
The discipline of drug discovery has greatly benefited by computational tools and in silico
algorithms aiming at rationalization of many related processes, from the stage of early hit …
algorithms aiming at rationalization of many related processes, from the stage of early hit …