Although RNA is generally thought to be a passive genetic blueprint, some RNA molecules,
called ribozymes, have intrinsic enzyme-like activity—they can catalyse chemical reactions …

▪ Abstract Mobile group II introns, found in bacterial and organellar genomes, are both
catalytic RNAs and retrotransposable elements. They use an extraordinary mobility …

Long non-coding RNAs (lncRNAs) are key regulatory molecules, but unlike with other RNAs,
the direct link between their tertiary structure motifs and their function has proven elusive …

It is becoming increasingly clear that RNA is more than a passive carrier of genetic
information. Folded RNA molecules play key roles in almost every aspect of cellular …

Group II introns have attracted considerable attention as ribozymes, mobile genetic
elements and possible progenitors of nuclear spliceosomal introns. Major advances in …

Long non-coding RNAs (lncRNAs) are recently-discovered transcripts that regulate vital
cellular processes and are crucially connected to diseases. Despite their unprecedented …

The function of many RNAs depends crucially on their structure. Therefore, the design of
RNA molecules with specific structural properties has many potential applications, eg in the …

Group II introns are large, autocatalytic ribozymes that catalyze RNA splicing and
retrotransposition. Splicing by group II introns plays a major role in the metabolism of plants …

Hydroxyl radical footprinting is a widely used method for following the folding of RNA
molecules in solution. This method has the unique ability to provide experimental …

Group II introns are large, natural catalytic RNAs or ribozymes that were discovered in
organelles of certain protists, fungi, algae, and plants and more recently also in prokaryotic …