Covering: up to 2013 Although holo-acyl carrier protein synthase, AcpS, a
phosphopantetheinyl transferase (PPTase), was characterized in the 1960s, it was not until …

Fluorescent probes have gained profound use in biotechnology, drug discovery, medical
diagnostics, molecular and cell biology. The development of methods for the translation of …

Acyl carrier protein (ACP) transports the growing fatty acid chain between enzymatic
domains of fatty acid synthase (FAS) during biosynthesis. Because FAS enzymes operate on …

Covering: up to April 5, 2018 Metabolites from type II fatty acid synthase (FAS) and
polyketide synthase (PKS) pathways differ broadly in their identities and functional roles …

Naturally occurring conjugated allenynes are of general interest owing to their potent and
various biological activities. The 1, 5‐H transfer of alka‐1, 4‐diyn‐3‐yl amines would be one …

Thioesters play essential roles in many biosynthetic pathways to fatty acids, esters,
polyketides, and non-ribosomal peptides. Coenzyme A (CoA) and related …

ACPs (acyl carrier proteins) play essential roles in the synthesis of fatty acids, polyketides
and non-ribosomal polypeptides. ACP function requires the modification of the protein by …

Covering: up to early 2018 The Nonribosomal Peptide Synthetases (NRPSs) and Polyketide
Synthases (PKSs) are families of modular enzymes that produce a tremendous diversity of …

Fatty acid biosynthesis is essential to life and represents one of the most conserved
pathways in nature, preserving the same handful of chemical reactions across all species …

Herein, we present a new desulfurative method for generating primary, secondary, and
tertiary alkyl radicals through visible‐light photoredox catalysis. A process that involves the …