Myeloid-derived suppressor cells (MDSCs) are a heterogenic population of immature
myeloid cells with immunosuppressive effects, which undergo massive expansion during …

Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and
monocytes with potent immunosuppressive activity. They are implicated in the regulation of …

Tumor Associated Neutrophils (TANs) are engaged into the tumor microenvironment by
cytokines and chemokines, can be distinguished according to their activation and cytokine …

Natural killer (NK) cells are a population of innate lymphoid cells playing a pivotal role in
host immune responses against infection and tumor growth. These cells have a powerful …

Smoking has a profound impact on tumor immunity, and nicotine, which is the major
addictive component of smoke, is known to promote tumor progression despite being a non …

Expression of high levels of immune cells including neutrophils has been associated with
detrimental outcome in several solid tumors and new strategies to decrease their presence …

Background Exosomes are extracellular vesicles that mediate cellular communication in
health and diseases. Neutrophils could be polarized to a pro-tumor phenotype by tumor. The …

Neutrophils are a vital component of immune protection, yet in cancer they may promote
tumour progression, partly by generating reactive oxygen species (ROS) that disrupts …

The tumor microenvironment (TME) is comprised of many different cell populations, such as
cancer-associated fibroblasts and various infiltrating immune cells, and non-cell …

Immune cells survey and patrol throughout the body and sometimes take residence in niche
environments with distinct cellular subtypes and nutrients that may fluctuate from those in …