Polyethylene glycol (PEG) conjugation is a rapidly evolving strategy to solve hurdles in
therapeutic delivery and is being used as an add-on tool to the traditional drug delivery …

Nonspecific protein adsorption and/or microbial adsorption on biomedical materials
adversely affects the efficacy of a range of biomedical systems, from implants and …

Abstract Poly (ethylene glycol)(PEG) is the most used polymer and also the gold standard for
stealth polymers in the emerging field of polymer‐based drug delivery. The properties that …

The paper discusses general problems in using PEG for conjugation to high or low
molecular weight molecules. Methods of binding PEG to different functional groups in …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are well recognized for
playing a dual role, since they can be either deleterious or beneficial to biological systems …

A series of α-functional maleimide polymethacrylates (M n= 4.1− 35.4 kDa, PDi= 1.06− 1.27)
have been prepared via copper-catalyzed living radical polymerization (LRP). Two …

Reactive Oxygen Species (ROS) are quintessential inflammatory compounds with oxidizing
behavior. We have successfully developed a micellar system with responsiveness at the …

Application of proteins and peptides as human therapeutics is expanding rapidly as drug
discovery becomes more prevalent. Conjugation of polymers to proteins can circumvent …

Without a doubt PEG–SOD has been the enzyme most studied in PEGylation. One can say
that it represents the preferred model to assess chemistries for PEG activation, analytical …

A comparative pharmacokinetic and biodistribution investigation of polymer− protein
conjugates prepared with various amphiphilic polymers was carried out using uricase as a …