Genome-wide association studies (GWAS) have revealed important biological insights into
complex diseases, which are broadly expected to lead to the identification of new drug …

Advanced and recurrent gynecological cancers are associated with poor prognosis and lack
of effective treatment. The developments of the molecular mechanisms on cancer …

A European consensus conference on endometrial carcinoma was held in 2014 to produce
multi-disciplinary evidence-based guidelines on selected questions. Given the large body of …

STUDY QUESTION How should fertility-sparing treatment of patients with endometrial
carcinoma be performed? SUMMARY ANSWER Forty-eight recommendations were …

The remit of this guideline is to collate and propose evidence-based guidelines for the
diagnosis and management of uterine cancer. This document covers all uterine cancers of …

Simple Summary Tamoxifen, an antiestrogen, is a potent drug to treat and prevent hormone
dependent breast cancer. As it has low toxicity and is widely available, tamoxifen has …

Rationale: Estrogen-dependent cancers (eg, breast, endometrial, and ovarian cancers) are
among the leading causes of morbidity and mortality in women worldwide. Recently …

The endometrium is a complex multicellular tissue that is exquisitely sensitive to the actions
of sex steroids synthesised in the ovary (endocrine system). Recent studies have highlighted …

Simple Summary Cervical cancer is the fourth most common cancer in women worldwide.
Tumour-related deaths are most frequent in low-and middle-income countries. Currently …

Patients with primary metastatic/recurrent endometrial cancer have poor prognosis and
available therapeutic options are limited. Current treatment is mainly based on platinum …