Accelerated reaction kinetics in microdroplets: Overview and recent developments
Various organic reactions, including important synthetic reactions involving C–C, C–N, and
C–O bond formation as well as reactions of biomolecules, are accelerated when the …
C–O bond formation as well as reactions of biomolecules, are accelerated when the …
Mass spectrometry-based protein footprinting for higher-order structure analysis: fundamentals and applications
Proteins adopt different higher-order structures (HOS) to enable their unique biological
functions. Understanding the complexities of protein higher-order structures and dynamics …
functions. Understanding the complexities of protein higher-order structures and dynamics …
Strong electric field observed at the interface of aqueous microdroplets
Chemical reactions in aqueous microdroplets often exhibit unusual kinetic and
thermodynamic properties not observed in bulk solution. While an electric field has been …
thermodynamic properties not observed in bulk solution. While an electric field has been …
Capture of hydroxyl radicals by hydronium cations in water microdroplets
Despite the high stability of bulk water, water microdroplets possess strikingly different
properties, such as the presence of hydroxyl radicals (OH⋅) at the air–water interface …
properties, such as the presence of hydroxyl radicals (OH⋅) at the air–water interface …
Harnessing the high interfacial electric fields on water microdroplets to accelerate Menshutkin reactions
Even though it is still an emerging field, the application of a high external electric field (EEF)
as a green and efficient catalyst in synthetic chemistry has recently received significant …
as a green and efficient catalyst in synthetic chemistry has recently received significant …
A critical analysis of electrospray techniques for the determination of accelerated rates and mechanisms of chemical reactions in droplets
Electrospray and Electrosonic Spray Ionization Mass Spectrometry (ESI-MS and ESSI-MS)
have been widely used to report evidence that many chemical reactions in micro-and nano …
have been widely used to report evidence that many chemical reactions in micro-and nano …
Abiotic production of sugar phosphates and uridine ribonucleoside in aqueous microdroplets
Phosphorylation is an essential chemical reaction for life. This reaction generates
fundamental cell components, including building blocks for RNA and DNA, phospholipids for …
fundamental cell components, including building blocks for RNA and DNA, phospholipids for …
Spontaneous formation of gold nanostructures in aqueous microdroplets
The synthesis of gold nanostructures has received widespread attention owing to many
important applications. We report the accelerated synthesis of gold nanoparticles (AuNPs) …
important applications. We report the accelerated synthesis of gold nanoparticles (AuNPs) …
Ultrafast enzymatic digestion of proteins by microdroplet mass spectrometry
Enzymatic digestion for protein sequencing usually requires much time, and does not
always result in high sequence coverage. Here we report the use of aqueous microdroplets …
always result in high sequence coverage. Here we report the use of aqueous microdroplets …
The role of analyte concentration in accelerated reaction rates in evaporating droplets
CJ Chen, ER Williams - Chemical science, 2023 - pubs.rsc.org
Accelerated reactions in microdroplets have been reported for a wide range of reactions with
some microdroplet reactions occurring over a million times faster than the same reaction in …
some microdroplet reactions occurring over a million times faster than the same reaction in …