Role of cholinergic signaling in Alzheimer's disease
ZR Chen, JB Huang, SL Yang, FF Hong - Molecules, 2022 - mdpi.com
Acetylcholine, a neurotransmitter secreted by cholinergic neurons, is involved in signal
transduction related to memory and learning ability. Alzheimer's disease (AD), a progressive …
transduction related to memory and learning ability. Alzheimer's disease (AD), a progressive …
Molecular targets of manganese-induced neurotoxicity: A five-year update
AA Tinkov, MMB Paoliello, AN Mazilina… - International journal of …, 2021 - mdpi.com
Understanding of the immediate mechanisms of Mn-induced neurotoxicity is rapidly
evolving. We seek to provide a summary of recent findings in the field, with an emphasis to …
evolving. We seek to provide a summary of recent findings in the field, with an emphasis to …
Consequences of disturbing manganese homeostasis
J Baj, W Flieger, A Barbachowska, B Kowalska… - International Journal of …, 2023 - mdpi.com
Manganese (Mn) is an essential trace element with unique functions in the body; it acts as a
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …
Environmental influence on neurodevelopmental disorders: Potential association of heavy metal exposure and autism
OM Ijomone, NF Olung, GT Akingbade… - Journal of Trace …, 2020 - Elsevier
Environmental factors have been severally established to play major roles in the
pathogenesis of neurodevelopmental disorders including autism spectrum disorder (ASD) …
pathogenesis of neurodevelopmental disorders including autism spectrum disorder (ASD) …
Manganese in the diet: bioaccessibility, adequate intake, and neurotoxicological effects
AC Martins, BN Krum, L Queirós… - Journal of agricultural …, 2020 - ACS Publications
Manganese (Mn) is an essential element that participates in several biological processes.
Mn serves as a cofactor for several enzymes, such as glutamine synthetase and …
Mn serves as a cofactor for several enzymes, such as glutamine synthetase and …
Manganese-induced neurodegenerative diseases and possible therapeutic approaches
AC Martins Jr, P Gubert, GR Villas Boas… - Expert review of …, 2020 - Taylor & Francis
Introduction Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's
disease, Huntington's disease, amyotrophic lateral sclerosis and prion disease represent …
disease, Huntington's disease, amyotrophic lateral sclerosis and prion disease represent …
New insights on the role of manganese in Alzheimer's disease and Parkinson's disease
Manganese (Mn) is an essential trace element that is naturally found in the environment and
is necessary as a cofactor for many enzymes and is important in several physiological …
is necessary as a cofactor for many enzymes and is important in several physiological …
Gut microbiota as a potential player in Mn-induced neurotoxicity
Manganese (Mn) is an essential metal, which at high exposures causes neurotoxic effects
and neurodegeneration. The neurotoxic effects of Mn are mediated by neuroinflammation …
and neurodegeneration. The neurotoxic effects of Mn are mediated by neuroinflammation …
Impact of environmental risk factors on mitochondrial dysfunction, neuroinflammation, protein misfolding, and oxidative stress in the etiopathogenesis of parkinson's …
As a prevalent progressive neurodegenerative disorder, Parkinson's disease (PD) is
characterized by the neuropathological hallmark of the loss of nigrostriatal dopaminergic …
characterized by the neuropathological hallmark of the loss of nigrostriatal dopaminergic …
Experimental models of chemically induced Parkinson's disease in zebrafish at the embryonic larval stage: a systematic review
P Briñez-Gallego, DG da Costa Silva… - Journal of Toxicology …, 2023 - Taylor & Francis
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of
dopaminergic neurons in the substantia nigra that results in a decrease in dopamine levels …
dopaminergic neurons in the substantia nigra that results in a decrease in dopamine levels …