Autophagy in traumatic brain injury: a new target for therapeutic intervention

L Zhang, H Wang - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Traumatic brain injury (TBI) is one of the most devastating forms of brain injury. Many
pathological mechanisms such as oxidative stress, apoptosis and inflammation all contribute …

Modulation of autophagy in traumatic brain injury

Z Zeng, Y Zhang, W Jiang, L He… - Journal of cellular …, 2020 - Wiley Online Library
Traumatic brain injury (TBI) is defined as a traumatically induced structural injury or
physiological disruption of brain function as a result of external forces, leading to adult …

Salubrinal offers neuroprotection through suppressing endoplasmic reticulum stress, autophagy and apoptosis in a mouse traumatic brain injury model

Z Wang, C Gao, W Chen, Y Gao, H Wang… - Neurobiology of learning …, 2019 - Elsevier
Traumatic brain injury (TBI) is a complex injury that can cause severe disabilities and even
death. TBI can induce secondary injury cascades, including but not limited to endoplasmic …

Mechanisms of cell–cell interaction in oligodendrogenesis and remyelination after stroke

K Itoh, T Maki, J Lok, K Arai - Brain research, 2015 - Elsevier
White matter damage is a clinically important aspect of several central nervous system
diseases, including stroke. Cerebral white matter primarily consists of axonal bundles …

Potential of food-derived bioactive peptides in alleviation and prevention of Alzheimer's disease

L Zhao, D Li, X Qi, K Guan, H Chen, R Wang, Y Ma - Food & Function, 2022 - pubs.rsc.org
Memory and cognitive impairment are the principal clinical symptoms of Alzheimer's disease
(AD). Cholinergic deficiency, amyloid-beta (Aβ) toxicity, tau protein hyperphosphorylation …

Naringenin attenuates endoplasmic reticulum stress, reduces apoptosis, and improves functional recovery in experimental traumatic brain injury

C Deng, R Yi, M Fei, T Li, Y Han, H Wang - Brain Research, 2021 - Elsevier
Traumatic brain injury (TBI) is a significant cause of disability and death worldwide.
Accumulating evidence suggests that endoplasmic reticulum (ER) stress would be an …

Protective effects of Humanin and calmodulin-like skin protein in Alzheimer's disease and broad range of abnormalities

M Matsuoka - Molecular neurobiology, 2015 - Springer
Humanin is a 24-amino acid, secreted bioactive peptide that prevents various types of cell
death and improves some types of cell dysfunction. Humanin inhibits neuronal cell death …

Humanin derivative, HNG, enhances neurotransmitter release

N Ikegawa, A Kozuka, N Morita, M Murakami… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Background Humanin (HN) is an endogenous 24-residue peptide that was first identified as
a protective factor against neuronal death in Alzheimer's disease (AD). We previously …

Humanin: a possible linkage between Alzheimer's disease and type 2 diabetes

H Mahboobi, J Golmirzaei, SH Gan… - CNS & Neurological …, 2014 - ingentaconnect.com
The prevalence of Alzheimer's disease (AD) is higher among type 2 diabetes mellitus
(T2DM) patients. In T2DM patients, the progression of AD is more rapid. Furthermore …

Glucocorticoid treatment inhibits intracerebral hemorrhage-induced inflammation by targeting the microRNA-155/SOCS-1 signaling pathway

HF Xu, XY Fang, SH Zhu, XH Xu… - Molecular …, 2016 - spandidos-publications.com
Intracerebral hemorrhage (ICH) results in inflammation, and glucocorticoids have been
proven to be effective inhibitors of ICH-induced inflammation. However, the precise …