The chemical stability of diphenhydramine (DIPH), azelastine (AZE) and bepotastine (BEPO)
was examined in solutions and solids. The drugs were subjected to high temperature (70° C …

Entrectinib is a potent inhibitor of receptor tyrosine kinases and anaplastic lymphoma
kinase. It is designated as an orphan drug. There exists no report of comprehensive …

Abstract Bepotastine (BPT), a second-generation antihistamine used for treating allergic
rhinitis and pruritus, requires precise dosage calculation and accurate measurement in …

Because of their topical application in patients and meaningful UV/VIS absorptive properties,
the degradation and potential toxicity under irradiation of diflunisal (DIF) and naphazoline …

Tazarotene is a prodrug that belongs to the acetylenic class of retinoids. The drug was
subjected to hydrolytic, oxidative and photolytic stress testing to establish its comprehensive …

Oxicams are important drugs that act as anti-inflammatory agents, of them, piroxicam and its
prodrugs are in daily use. The metabolic profiles of oxicams were explored using mass …

Bepotastine, a second-generation antihistamine for allergic rhinitis and urticaria, is widely
used in all age groups but lacks appropriate dosing guidelines for pediatric patients, leading …

Venetoclax (VEN), an anticancer drug, was subjected to photolytic and oxidative
degradation studies. The comprehensive degradation profiling of VEN in both conditions …

Rationale Stress testing on tinoridine hydrochloride was carried out using a
multidimensional approach. This included different conditions: hydrolytic (acidic, alkaline …

Timolol (TIM) is a non-selective ß-adrenergic receptor antagonist used orally for the
treatment of hypertension and heart attacks, and topically for treating glaucoma; lately, it has …