Systems chronotherapeutics

A Ballesta, PF Innominato, R Dallmann, DA Rand… - Pharmacological …, 2017 - ASPET
Chronotherapeutics aim at treating illnesses according to the endogenous biologic rhythms,
which moderate xenobiotic metabolism and cellular drug response. The molecular clocks …

Yoga for symptom management in oncology: a review of the evidence base and future directions for research

SC Danhauer, EL Addington, L Cohen, SJ Sohl… - Cancer, 2019 - Wiley Online Library
Because yoga is increasingly recognized as a complementary approach to cancer symptom
management, patients/survivors and providers need to understand its potential benefits and …

The relationship between pro-inflammatory cytokines and pain, appetite and fatigue in patients with advanced cancer

Ø Paulsen, B Laird, N Aass, T Lea, P Fayers, S Kaasa… - PloS one, 2017 - journals.plos.org
Background Systemic inflammation is associated with reduced quality of life and increased
symptoms in patients with advanced cancer. The aims of this study were to examine the …

Cancer‐related impairments and functional limitations among long‐term cancer survivors: gaps and opportunities for clinical practice

L Nekhlyudov, GB Campbell, KH Schmitz, GA Brooks… - Cancer, 2022 - Wiley Online Library
This commentary provides a concise overview of the epidemiology of cancer survivorship
and work, common functional limitations experienced by cancer survivors, and evidence …

Parallel and serial mediation analysis between pain, anxiety, depression, fatigue and nausea, vomiting and retching within a randomised controlled trial in patients …

A Charalambous, M Giannakopoulou, E Bozas… - BMJ open, 2019 - bmjopen.bmj.com
Objective Cancer treatment is a particularly stressful period for the patient. The reasons vary
and include fear of treatment outcome as well as treatment induced side effects. The patient …

Stability of symptom clusters in patients with lung cancer receiving chemotherapy

J Russell, ML Wong, L Mackin, SM Paul… - Journal of pain and …, 2019 - Elsevier
Context Patients with lung cancer who undergo chemotherapy (CTX) experience multiple
symptoms. Evaluation of how these symptoms cluster together and how these symptom …

Symptom clusters during palliative chemotherapy and their influence on functioning and quality of life

SY Rha, J Lee - Supportive Care in Cancer, 2017 - Springer
Introduction Symptom management in patients undergoing palliative chemotherapy is
challenging, as patients may suffer from cancer symptoms as well as symptoms related to …

Symptom clusters in newly diagnosed glioma patients: which symptom clusters are independently associated with functioning and global health status?

MB Coomans, L Dirven, NK Aaronson… - Neuro …, 2019 - academic.oup.com
Background Symptom management in glioma patients remains challenging, as patients
suffer from various concurrently occurring symptoms. This study aimed to identify symptom …

Relationship among symptom clusters, quality of life, and treatment-specific optimism in patients with cancer

M Matzka, S Köck-Hódi, P Jahn, H Mayer - Supportive Care in Cancer, 2018 - Springer
Purpose There is increasing evidence that disease and therapy-related symptoms frequently
co-occur in so-called symptom clusters (SCs), which may significantly impair quality of life in …

THALIS: Human-machine analysis of longitudinal symptoms in cancer therapy

C Floricel, N Nipu, M Biggs, A Wentzel… - … on Visualization and …, 2021 - ieeexplore.ieee.org
Although cancer patients survive years after oncologic therapy, they are plagued with long-
lasting or permanent residual symptoms, whose severity, rate of development, and …