Small-molecule self-assembly is an established route for producing high-surface-area
nanostructures with readily customizable chemistries and precise molecular organization …

Synthetic peptide and peptido-mimetic filaments and tubes represent a diverse class of
nanomaterials with a broad range of potential applications, such as drug delivery, vaccine …

Abstract α-Synuclein aggregation underlies pathological changes in Lewy body dementia.
Recent studies highlight structural variabilities associated with α-synuclein aggregates in …

We perform molecular dynamics simulation on several relevant biological fibrils associated
with neurodegenerative diseases such as Aβ 40, Aβ 42, and α-synuclein systems to obtain a …

Alpha-helices and beta-sheets are the two most common secondary structure motifs in
proteins. Beta-helical structures merge features of the two motifs, containing two or three …

Biomolecular self-assembly is an emerging bottom-up approach for the synthesis of novel
nanomaterials. DNA and viruses have both been used to create scaffolds but the former …

Solid interfacing biomaterials is a crucial aspect of bionanotechnology and important for
applications such as biosensing. Because of their potentially large contact area, flat …

Self-assembly of small molecules in water provides a bottom-up strategy to generate highly
ordered nanostructures with dimensions on molecular (< 10 nm) length scales. However …

Amyloid fibrils are found in almost all aspects of life and are often associated with neurotoxic
effects as in eg Alzheimer's disease. Exemplary, fibrils can also perform functional tasks …

2023-03-10 Assigned to THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
reassignment THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ASSIGNMENT OF …