[HTML][HTML] Molecular mechanism of α-Hederin in tumor progression

D Meng, M Ren, M Li, M Wang, W Geng… - Biomedicine & …, 2024 - Elsevier
Abstract α-Hederin is a monosaccharide pentacyclic triterpene saponin compound derived
from the Chinese herb, Pulsatilla. It has garnered considerable attention for its anti-tumor …

Antitumor activity and targeting p53-PUMA mRNA expression by 5-flurouracil PLGA-lipid polymeric nanoparticles in mouse mammary carcinomas: comparison to free …

ST Alsharif, AM Gardouh, MF Mandour… - Toxicology …, 2024 - Taylor & Francis
Polymeric poly (lactic-co-glycolic acid)(PLGA)-lipid hybrid nanoparticles (PNPs)-based
therapy are powerful carriers for various therapeutic agents. This study was conducted to …

[PDF][PDF] α-常春藤皂苷通过激活和稳定p53/Noxa信号诱导肝癌细胞凋亡*

陈晓静, 周莉, 刘凯琪, 段菊凤, 刘明, 李洪亮, 汪选斌 - 医药导报, 2024 - yydbzz.com
目的研究预知子活性成分α-常春藤皂苷对肝癌细胞的体内外抑制作用及其机制.
方法将肝癌细胞分为4 组, 分别给予0, 10, 20 和30 μmol· L-1 α-常春藤皂苷至24, 48 h …

Herbal Medicine and Plants in the Treatment of Leukemia

A Boro, AJ Dheivasikamani, VA Arumugam… - … Medicinal Plants in …, 2024 - igi-global.com
Herbs and derived medicines are traditionally practiced in many regions worldwide. The
components present in the plant are known as secondary metabolites that have many …

[PDF][PDF] α-Hederin Induces Apoptosis in Hepato-cellular Carcinoma Cells by Activating and Stabilizing p53/Noxa Signaling Pathway

C Xiaojing, Z Li, LIU Kaiqi, D Jufeng, LIU Ming… - Herald of …, 2024 - yydbzz.com
Objective To investigate the inhibitory effects and mechanisms of α-hederin, an active
ingredient in Fructus Akebiae, on hepatocellular carcinoma (HCC) cells. Methods HCC cells …

[引用][C] Ethnomedicinal uses, phytochemistry, and cytotoxic potential of Polyscias fulva

SB Tankeo, V Kuete - 2024 - Elsevier