Food-derived peptides, as dietary supplements, have significant effects on promoting brain
health and relieving central nervous system (CNS) diseases. However, the blood–brain …

Microbe-induced meningoencephalitis/meningitis is a life-threatening infection of the central
nervous system (CNS) that occurs when pathogens are able to cross the blood-brain barrier …

Coxsackievirus B3 (CVB3) is a significant human pathogen that is commonly found
worldwide. CVB3 among other enteroviruses, are the leading causes of aseptic meningo …

The human blood–brain barrier (BBB) comprises a single layer of brain microvascular
endothelial cells (HBMECs) protecting the brain from bloodborne pathogens. Meningitis is …

Glaesserella parasuis (G. parasuis) can elicit meningitis in pigs; however, the pathogenic
mechanisms of meningitis induced by G. parasuis remain unclear. Long non-coding RNAs …

Controversies surrounding the validity of the toxic proteinopathy theory of Alzheimer's
disease have led the scientific community to seek alternative theories in the pathogenesis of …

Cryptococcus neoformans can invade the central nervous system by crossing the blood-
brain barrier via a transcellular mechanism that relies on multiple host factors. In this …

Di (2-ethhylhexyl) phthalate (DEHP) is a common plastic rubberizer. DEHP leaches from
plastic matrices and is under increasing scrutiny as numerous studies have linked it to …

Clostridioides difficile is the main causative agent of hospital-acquired diarrhea and the
potentially lethal disease, C. difficile infection. The cornerstone of the current therapy is the …

Lyme disease, caused by Borrelia (or Borreliella) burgdorferi, is a complex multisystemic
disorder that includes Lyme neuroborreliosis resulting from the invasion of both the central …