Interferon alpha (IFN-α) is a glycoprotein with antitumor, antiviral, and immunomodulatory
activity, used widely in the treatment of viral infections (hepatitis B and C, condylomata …

Corneal pathologies are a major cause of blindness and visual impairment, especially in the
developing world. However, not only is there a global shortage of donor corneal tissue, but a …

Purpose: The aim of this study was to characterize a large cohort of patients presenting to a
single referral center for limbal stem cell deficiency (LSCD). Methods: A retrospective chart …

Limbal stem cell deficiency (LSCD) can cause significant corneal vascularization and
scarring and often results in serious visual morbidity. An early and accurate diagnosis can …

Diabetic retinopathy (DR) is one of the major causes of visual impairment and irreversible
blindness in developed regions. Aside from abnormal angiogenesis, inflammation is the …

Abstract Limbal Stem Cell Deficiency (LSCD), caused due to corneal injury, primarily by
chemical/alkali burns, leads to compromised vision. Recently, several animal models of …

Sulfur mustard (SM) is a strong blistering, highly reactive, lipophilic chemical war agent that
causes injury in different organs including the skin, eyes, and respiratory tract. The Eyes are …

Nanotargeting delivery system is recently much more attention for delivering drugs and
bioactive compounds to treating ocular diseases. Here, the Guar gum (GG) armed drug …

Purpose To investigate the toxicity of type I interferons (IFNs) on the ocular surface and
assess their efficacy in ocular surface tumors. Methods We examined the effects of IFN-α2a …

Vitamin A is an essential fat-soluble vitamin that cannot be endogenously synthesized by the
human body. Retinoic acid (RA) is the biologically active form of vitamin A. Utilizing both …