In this review we compare and discuss results of compounds already reported as anticancer
agents based on isatin-derivatives, metalated as well as non-metallated. Isatin compounds …

Abstract Isatin (indole‐2, 3‐dione) is an oxidized indole. It is widely distributed in
mammalian tissues and body fluids, where isatin concentrations vary significantly from< 0.1 …

Isatin derivatives potentially act on various biological targets. In this article, a series of novel
isatin-hydrazones were synthesized in excellent yields. Their cytotoxicity was tested against …

Thymidine phosphorylase (TP) is an angiogenic enzyme. It plays an important role in
angiogenesis, tumour growth, invasion and metastasis. In current research work, we study …

In connection with our research program on the development of new isatin-based anticancer
candidates, herein we report the synthesis of two novel series of thiazolidinone-isatin …

Indoline framework is often perpended as a privileged heterocycle present in medicinally
valuable compounds of natural and synthetic origin. This review article presents the rational …

Background Hydrazide derivatives constitute an important class of compounds for new drug
development as they are reported to possess good anti-inflammatory and analgesic activity …

A series of spirochromenocarbazole tethered 1, 2, 3-triazoles were synthesized via click
chemistry based one-pot, five component reaction between N-propargyl isatins …

A series of isatin Schiff base derivatives were identified during in silico screening of the
small molecule library for novel activators of p53. The compounds selected based on …

Background: Isatin (IST) is a crucial pharmacologically active compound, chemically known
as indole-1H-2, 3-dione. Development of different IST based analogues acquired significant …