Animal models of fibromyalgia: What is the best choice?

ES Brum, G Becker, MFP Fialho, SM Oliveira - Pharmacology & …, 2022 - Elsevier
Fibromyalgia (FM) is a complex syndrome, with an indefinite aetiology and intricate
pathophysiology that affects 2–3% of the world population. From the beginning of the 2000s …

Considerations of medical preparedness to assess and treat various populations during a radiation public health emergency

TA Winters, DR Cassatt… - Radiation …, 2023 - meridian.allenpress.com
During a radiological or nuclear public health emergency, given the heterogeneity of civilian
populations, it is incumbent on medical response planners to understand and prepare for a …

A standardization of the novelty-suppressed feeding test protocol in rats

A Blasco-Serra, EM González-Soler, A Cervera-Ferri… - Neuroscience …, 2017 - Elsevier
Tests based on hyponeophagia phenomena are the most widely used to check the efficacy
and efficiency of new-generation chronic antidepressant treatments. Even so, these tests …

[HTML][HTML] Chemogenetic Activation of Oxytocin Neurons Improves Pain in a Reserpine-induced Fibromyalgia Rat Model

N Ikeda, M Kawasaki, K Baba, H Nishimura, T Fujitani… - Neuroscience, 2023 - Elsevier
Fibromyalgia (FM) is a syndrome characterized by chronic pain with depression as a
frequent comorbidity. However, efficient management of the pain and depressive symptoms …

Stem cells therapeutic effect in a reserpine-induced fibromyalgia rat model: A possible NLRP3 inflammasome modulation with neurogenesis promotion in the cerebral …

SA Mokhemer, MK Desouky, AK Abdelghany… - Life Sciences, 2023 - Elsevier
Fibromyalgia is a chronic pain syndrome with a multifactorial pathophysiology affecting 2–
8% of the population. Aims To investigate the therapeutic effects of bone marrow …

Pramipexole, a dopamine D3/D2 receptor-preferring agonist, attenuates reserpine-induced fibromyalgia-like model in mice

CP Martins, RS Paes, GM Baldasso… - Neural Regeneration …, 2022 - journals.lww.com
Fibromyalgia (FM) is a complex pathology described as persistent hyperalgesia including
somatic and mood dysfunctions, depression and anxiety. Although the etiology of FM is still …

[PDF][PDF] Chronic pregabalin treatment ameliorates pain, but not depressive-like behaviors, in a reserpine-induced myalgia model in rats

EM Gonzalez-Soler, A Blasco-Serra… - Pain …, 2020 - painphysicianjournal.com
Background: Anticonvulsants are often prescribed as coanalgesics for pathologies
presenting chronic pain, such as chronic neuropathic pain and fibromyalgia. These …

Nano-pregabalin effectively mitigates Glut, CGRP and NE neurotransmitters abnormalities in the brain of gamma irradiated rats with reserpine-induced fibromyalgia …

EM Samy, RR Radwan, FM Mosallam, HA Mohamed - Neuropharmacology, 2024 - Elsevier
Aims Fibromyalgia (FM) is an idiopathic syndrome with painful burdensome symptoms.
Radiotherapy is one of the main therapeutic modalities for treating various malignancies and …

Novel insights into the molecular mechanisms underlying anti-nociceptive effect of myricitrin against reserpine-induced fibromyalgia model in rats: Implication of SIRT1 …

AS Aboutaleb, A Allam, HS Zaky, MF Harras… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Manilkara zapota (L.) P. Royen, also termed sapodilla or
chikoo, is a significant plant in ethnomedicine because of its long history of traditional …

Amitriptyline and duloxetine attenuate activities of superficial dorsal horn neurons in a rat reserpine-induced fibromyalgia model

D Uta, K Tsuboshima, K Mizumura, H Nishijo… - Journal of …, 2024 - Elsevier
Fibromyalgia (FM) is an intractable disease with a chief complaint of chronic widespread
pain. Amitriptyline (AMI) and duloxetine (DLX), which are antidepressant drugs, have been …