[HTML][HTML] The controversial role of HCY and vitamin B deficiency in cardiovascular diseases

W Herrmann, M Herrmann - Nutrients, 2022 - mdpi.com
Plasma homocysteine (HCY) is an established risk factor for cardiovascular disease CVD
and stroke. However, more than two decades of intensive research activities has failed to …

Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity

M Fenech - … Research/Fundamental and Molecular Mechanisms of …, 2012 - Elsevier
Folate plays a critical role in the prevention of uracil incorporation into DNA and
hypomethylation of DNA. This activity is compromised when vitamin B12 concentration is …

Folates and aging: Role in mild cognitive impairment, dementia and depression

JR Araújo, F Martel, N Borges, JM Araújo… - Ageing research …, 2015 - Elsevier
In almost all tissues, including the brain, folates are required for one-carbon transfer
reactions, which are essential for the synthesis of DNA and RNA nucleotides, the …

[HTML][HTML] Association of nutraceutical supplements with longer telomere length

D Tsoukalas, P Fragkiadaki… - International …, 2019 - spandidos-publications.com
Telomeres are nucleotide tandem repeats located at the tip of eukaryotic chromosomes that
maintain genomic integrity. The gradual shortening of telomeres leads to cellular …

[HTML][HTML] Subclinical inflammation, telomere shortening, homocysteine, vitamin B6, and mortality: the Ludwigshafen Risk and Cardiovascular Health Study

I Pusceddu, W Herrmann, ME Kleber… - European journal of …, 2020 - Springer
Purpose Short telomeres and B vitamin deficiencies have been proposed as risk factors for
age-related diseases and mortality that interact through oxidative stress and inflammation …

[HTML][HTML] Preterm Birth and its association with maternal diet, and placental and neonatal telomere length

N Lis, D Lamnisos, A Bograkou-Tzanetakou… - Nutrients, 2023 - mdpi.com
Preterm birth (PTB), a multi-causal syndrome, is one of the global epidemics. Maternal
nutrition, but also neonatal and placental telomere length (TL), are among the factors …

[HTML][HTML] Nutrition and lifestyle in healthy aging: the telomerase challenge

V Boccardi, G Paolisso, P Mecocci - Aging (Albany NY), 2016 - ncbi.nlm.nih.gov
Nutrition and lifestyle, known to modulate aging process and age-related diseases, might
also affect telomerase activity. Short and dysfunctional telomeres rather than average …

Zinc supplementation influences genomic stability biomarkers, antioxidant activity, and zinc transporter genes in an elderly Australian population with low zinc status

R Sharif, P Thomas, P Zalewski… - Molecular nutrition & …, 2015 - Wiley Online Library
Scope An increased intake of Zinc (Zn) may reduce the risk of degenerative diseases but
may prove to be toxic if taken in excess. This study aimed to investigate whether zinc …

[HTML][HTML] Folate deficiency as predisposing factor for childhood leukaemia: a review of the literature

CD Cantarella, D Ragusa, M Giammanco, S Tosi - Genes & nutrition, 2017 - Springer
Background Folic acid and its derivates, known as folates, are chemoprotective
micronutrients of great interest because of their essential role in the maintenance of health …

Maternal folate concentration in early pregnancy and newborn telomere length

S Entringer, ES Epel, J Lin, EH Blackburn… - Annals of Nutrition and …, 2015 - karger.com
Abstract Background/Aims: Telomere biology plays a fundamental role in genomic integrity
and cell physiology. The newborn setting of telomere length (TL) likely has important …