During the last two to three decades our understanding of the immunobiology of periodontal
disease has increased exponentially, both with respect to the microbial agents triggering the …

During the last decade, biological therapies have an increasing share in the modern
therapeutics of various diseases including inflammatory bowel diseases (IBD). Animal …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Background Macrophages are key players in inflammatory bowel diseases (IBD). This study
aimed to determine site-specific effects of defined macrophage subtypes on the integrity of …

BACKGROUND & AIMS: Prolyl and asparaginyl hydroxylases are key oxygen-sensing
enzymes that confer hypoxic sensitivity to transcriptional regulatory pathways including the …

Microbial dysbiosis has long been postulated to be associated with the pathogenesis of
inflammatory bowel disease (IBD). Although evidence supporting the anti-colitic effects of …

Dehydroepiandrosterone (DHEA) is a popular dietary supplement that has anti-
inflammatory, anti-oxidant and immune-regulating role; meanwhile, it also can effective in …

We identified biologically relevant moderators of response to tumor necrosis factor (TNF)-α
inhibitor, infliximab, among 60 individuals with bipolar depression. Data were derived from a …

Soybean meal-induced enteritis (SBMIE) is a well-described condition in the distal intestine
(DI) of several cultured fish species, but the exact cause is still unclear. The work on Atlantic …

Abstract Background and Aim Nuclear factor kappa B (NF‐κB) activation and endoplasmic
reticulum (ER) stress signaling play significant roles in the pathogenesis of inflammatory …