Chemotherapy versus surgery for initial treatment in advanced ovarian epithelial cancer

SL Coleridge, A Bryant, S Kehoe… - Cochrane Database of …, 2021 - cochranelibrary.com
Background Epithelial ovarian cancer presents at an advanced stage in the majority of
women. These women require surgery and chemotherapy for optimal treatment …

Neoadjuvant chemotherapy before surgery versus surgery followed by chemotherapy for initial treatment in advanced ovarian epithelial cancer

SL Coleridge, A Bryant, S Kehoe… - Cochrane Database of …, 2021 - cochranelibrary.com
Background Epithelial ovarian cancer presents at an advanced stage in the majority of
women. These women require a combination of surgery and chemotherapy for optimal …

[HTML][HTML] How do familiarity and fatal accidents affect acceptance of self-driving vehicles?

M Wicki - Transportation research part F: traffic psychology and …, 2021 - Elsevier
Expected benefits of disruptive technologies such as self-driving vehicles may only
materialize if they are publicly accepted. Acceptance increases when implementation is …

Association between overall survival and the tendency for cancer programs to administer neoadjuvant chemotherapy for patients with advanced ovarian cancer

A Melamed, JA Rauh-Hain, AA Gockley… - JAMA …, 2021 - jamanetwork.com
Importance Randomized clinical trials have found that, in patients with advanced-stage
epithelial ovarian cancer, neoadjuvant chemotherapy has similar long-term survival and …

The effect of influenza vaccination for the elderly on hospitalization and mortality: an observational study with a regression discontinuity design

ML Anderson, C Dobkin, D Gorry - Annals of Internal Medicine, 2020 - acpjournals.org
Background: Observational studies using traditional research designs suggest that influenza
vaccination reduces hospitalizations and mortality among elderly persons. Accordingly …

Primary cytoreductive surgery for advanced stage endometrial cancer: a systematic review and meta-analysis

BB Albright, KA Monuszko, SJ Kaplan… - American journal of …, 2021 - Elsevier
Objective Endometrial cancer uncommonly presents at an advanced stage and little
prospective evidence exists to guide the management thereof. We aimed to summarize the …

[HTML][HTML] Prehabilitation for medically frail patients undergoing surgery for epithelial ovarian cancer: a cost-effectiveness analysis

J Dholakia, DE Cohn, JM Straughn Jr… - Journal of Gynecologic …, 2021 - ncbi.nlm.nih.gov
Objective To assess the potential cost-effectiveness of prehabilitation in medically frail
patients undergoing surgery for epithelial ovarian cancer (EOC). Methods We created a cost …

Interval debulking surgery is not worth the wait: a National Cancer Database study comparing primary cytoreductive surgery versus neoadjuvant chemotherapy

YA Lyons, HD Reyes, ME McDonald… - International Journal of …, 2020 - ijgc.bmj.com
Objective In previous studies, neoadjuvant chemotherapy followed by interval debulking
surgery was not inferior to primary cytoreductive surgery as initial treatment for advanced …

Modulation of RAB7A protein expression determines resistance to cisplatin through late endocytic pathway impairment and extracellular vesicular secretion

F Guerra, A Paiano, D Migoni, G Girolimetti… - Cancers, 2019 - mdpi.com
Background: Cisplatin (CDDP) is widely used in treatment of cancer, yet patients often
develop resistance with consequent therapeutical failure. In CDDP-resistant cells alterations …

Development and validation of a risk-calculator for adverse perioperative outcomes for women with ovarian cancer

S Cham, L Chen, CMS Clair, JY Hou, AI Tergas… - American journal of …, 2019 - Elsevier
Background Primary cytoreduction followed by platinum-based chemotherapy is the primary
treatment for advanced ovarian cancer. However, neoadjuvant chemotherapy followed by …