Background Pulmonary arterial hypertension (PAH) is a group of vascular diseases that
produce right ventricular dysfunction, heart failure syndrome, and death. Although the …

Endothelin-1,(ET-1, EDN1) is an endogenous polypeptide which demonstrates dominant
vasoconstriction activity and mitogenic effect. It has positive inotropic and chronotropic …

Despite recent improvements in management of idiopathic pulmonary arterial hypertension,
mortality remains high. Understanding the alterations in the transcriptome–phenotype of the …

Background The influence of 5-HTT, BMPR2, EDN1, ENG, KCNA5 genes polymorphisms on
susceptibility of pulmonary arterial hypertension remains uncertain. This meta-analysis is …

Background: Health disparities have a major impact in the quality of life and clinical care
received by minorities in the United States. Pulmonary arterial hypertension (PAH) is a rare …

Endothelin-1 (ET-1) and adrenomedullin (ADM) are circulating vasoactive peptides involved
in vascular homeostasis and endothelial function. Elevated levels of plasma ET-1 and ADM …

Abstract Background: Endothelin-1 (ET-1), a potent endogenous vasoconstrictor, stimulates
production of reactive oxygen species. Endothelial monocyte-activating polypeptide-II …

Tibetan chickens have unique adaptations to the extreme high-altitude environment that
they inhabit. Epigenetic DNA methylation affects many biological processes, including …

The aim of this study was to evaluate the interacted association between EDNRA and EDN1
polymorphisms and gender, regular exercise, and obesity status on carotid intima media …

Results The ET-1 plasma level was significantly higher in the H+ A+ group in comparison
with the other groups, especially H+ A–. Comparing people with CA and those without it, the …