Protein tyrosine phosphatase receptor zeta 1 as a potential target in cancer therapy and diagnosis

E Papadimitriou, VK Kanellopoulou - International Journal of Molecular …, 2023 - mdpi.com
Protein tyrosine phosphatase receptor zeta 1 (PTPRZ1) is a type V transmembrane tyrosine
phosphatase that is highly expressed during embryonic development, while its expression …

Nanotechnology at the crossroads of stem cell medicine

S Jain, J Bhatt, S Gupta, DD Bhatia - Biomaterials Science, 2025 - pubs.rsc.org
Nanotechnology is transforming stem cell medicine by enabling precise isolation, controlled
differentiation, and targeted therapies across various medical domains. This review …

Chip collection of hepatocellular carcinoma based on O2 heterogeneity from patient tissue

S Baek, HS Ha, JS Park, MJ Cho, HS Kim… - Nature …, 2024 - nature.com
Hepatocellular carcinoma frequently recurs after surgery, necessitating personalized clinical
approaches based on tumor avatar models. However, location-dependent oxygen …

Artificial Vasa‐Vasorum Serves as an On‐Site Regenerative Promoter of Cell‐Free Vascular Grafting

H Ha, S Baek, K Lee, S Cho, MJ Cho… - Advanced Functional …, 2024 - Wiley Online Library
The control paradigm of small vessel pathophysiology has changed to focus on the vascular
out‐wall rather than the lumen‐intimal factors. As an emerging controller of the external wall …

In Situ Reprogrammings of Splenic CD11b+ Cells by Nano‐Hypoxia to Promote Inflamed Damage Site‐Specific Angiogenesis

S Chung, SY Kim, K Lee, S Baek, HS Ha… - Advanced Functional …, 2023 - Wiley Online Library
Clinical translation of nanoparticles is limited because of their short circulation time, which
hampers targeting to prolong therapeutic effects. Angiogenesis is required to regenerate …

Genetic deletion or tyrosine phosphatase inhibition of PTPRZ1 activates c‐Met to up‐regulate angiogenesis and lung adenocarcinoma growth

P Kastana, D Ntenekou, E Mourkogianni… - … Journal of Cancer, 2023 - Wiley Online Library
Protein tyrosine phosphatase receptor zeta 1 (PTPRZ1) is a transmembrane tyrosine
phosphatase (TP) expressed in endothelial cells and required for stimulation of cell …

[HTML][HTML] Disruption of bioenergetics enhances the radio-sensitivity of patient-derived glioblastoma tumorspheres

SJ Kim, J Park, J Shim, RJ Choi, JH Moon, EH Kim… - Translational …, 2025 - Elsevier
Background Despite available treatment approaches, including surgical resection along with
chemotherapy and radiotherapy, glioblastoma (GBM), the most prevalent primary brain …

Synergistic combination of perphenazine and temozolomide suppresses patient-derived glioblastoma tumorspheres

JP Hong, RJ Choi, JK Shim, K Kim, RN Kim… - Neuro …, 2024 - academic.oup.com
Background Glioblastoma (GBM), a primary malignant brain tumor, has a poor prognosis,
even with standard treatments such as radiotherapy and chemotherapy. In this study, we …

Intercellular aspirin hand-over with dual therapies by liposome-loaded monocytes

HJ Sung, SE Yu, J Kim, DH Kim, S Baek, S Park… - 2024 - researchsquare.com
Cell-cell communication serves as a foundation concept of intercellular therapeutic hand-
over. Despite the commonsense level of understanding, no clear projection has been made …

Chip collection of hepatocellular carcinoma based on O2 heterogeneity from patient tissue

HJ Sung, S Baek, HS Ha, JS Park, HS Kim, S Chung… - 2024 - researchsquare.com
As hepatocellular carcinoma (HCC) recurs even after surgical operation, tumor avatar
models have been suggested to approach the HCC type-specified clinical strategy …