Polybrominated diphenyl ethers (PBDEs), extensively used in the past few decades as flame
retardants in a variety of consumer products, have become world-wide persistent …

Background/objective: Polybrominated diphenyl ethers (PBDEs) and their hydroxylated (OH-
) or methoxylated forms have been detected in humans. Because this raises concern about …

Organophosphate flame retardants (OPFRs) are used as replacements for the commercial
PentaBDE mixture that was phased out in 2004. OPFRs are ubiquitous in the environment …

Background: Polybrominated diphenyl ethers (PBDEs) are persistent, bioaccumulative, and
endocrine-disrupting chemicals. Objectives: We used handwipes to estimate exposure to …

Elevated extracellular potassium chloride is widely used to achieve membrane
depolarization of cultured neurons. This technique has illuminated mechanisms of calcium …

Polybrominated diphenyl ether (PBDE) flame retardants have become ubiquitous
environmental pollutants. The relatively higher body burden in toddlers and children has …

Brominated flame retardants (BFRs) are widely used chemicals that prevent or slow the
onset and spreading of fire. Unfortunately, many of these compounds pose serious threats …

Environmental pollution often releases multiple contaminants resulting in as yet largely
uncharacterized additive toxicities. Cadmium (Cd) is a widespread pollutant that induces …

Background: Previous studies have indicated that cytochrome P450s (CYPs) are involved in
the metabolism of polybrominated diphenyl ether (PBDE) flame retardants in humans …

The developing nervous system is particularly vulnerable to chemical insults. Exposure to
chemicals can result in neurobehavioural alterations, and these have been used as …