Polygenic risk scores for cardiovascular disease: a scientific statement from the American Heart Association

JW O'Sullivan, S Raghavan, C Marquez-Luna… - Circulation, 2022 - Am Heart Assoc
Cardiovascular disease is the leading contributor to years lost due to disability or premature
death among adults. Current efforts focus on risk prediction and risk factor mitigation ‚which …

A synopsis of the evidence for the science and clinical management of cardiovascular-kidney-metabolic (CKM) syndrome: a scientific statement from the American …

CE Ndumele, IJ Neeland, KR Tuttle, SL Chow… - Circulation, 2023 - Am Heart Assoc
A growing appreciation of the pathophysiological interrelatedness of metabolic risk factors
such as obesity and diabetes, chronic kidney disease, and cardiovascular disease has led …

Independent association of lipoprotein (a) and coronary artery calcification with atherosclerotic cardiovascular risk

A Mehta, N Vasquez, CR Ayers, J Patel… - Journal of the American …, 2022 - jacc.org
Abstract Background Elevated lipoprotein (a)[Lp (a)] and coronary artery calcium (CAC)
score are individually associated with increased atherosclerotic cardiovascular disease …

Coronary computed tomography angiography-based calcium scoring: in vitro and in vivo validation of a novel virtual noniodine reconstruction algorithm on a clinical …

T Emrich, G Aquino, UJ Schoepf, FM Braun… - Investigative …, 2022 - journals.lww.com
Purpose The aim of this study was to evaluate coronary computed tomography angiography
(CCTA)-based in vitro and in vivo coronary artery calcium scoring (CACS) using a novel …

Association between triglyceride glucose index, coronary artery calcification and multivessel coronary disease in Chinese patients with acute coronary syndrome

J Wang, X Huang, C Fu, Q Sheng, P Liu - Cardiovascular diabetology, 2022 - Springer
Background Multivessel coronary disease (MVCD) is the common type of coronary artery
disease in acute coronary syndrome (ACS). Coronary artery calcification (CAC) has been …

Hyperlipidemia and cardiovascular risk in children and adolescents

F Mainieri, S La Bella, F Chiarelli - Biomedicines, 2023 - mdpi.com
Atherosclerotic cardiovascular disease (ASCVD) represents the major cause of morbidity
and mortality worldwide. The onset of the atherosclerosis process occurs during childhood …

Ischemic Heart Disease in Young Women: JACC Review Topic of the Week

MB Minissian, PK Mehta, SN Hayes, K Park… - Journal of the American …, 2022 - jacc.org
Abstract The Cardiovascular Disease in Women Committee of the American College of
Cardiology convened a working group to develop a consensus regarding the continuing rise …

LP (a): structure, genetics, associated cardiovascular risk, and emerging therapeutics

E Tasdighi, R Adhikari, O Almaadawy… - Annual Review of …, 2024 - annualreviews.org
Lipoprotein (a)[Lp (a)] is a molecule bound to apolipoprotein (a) with some similarity to low-
density lipoprotein cholesterol (LDL-C), which has been found to be a risk factor for …

Coronary artery calcium versus pooled cohort equations score for primary prevention guidance: randomized feasibility trial

JB Muhlestein, KU Knowlton, VT Le, DL Lappe… - Cardiovascular …, 2022 - jacc.org
Objectives This study sought to determine the feasibility of performing an extensive
randomized outcomes trial comparing a coronary artery calcium (CAC)-versus a pooled …

Toxic metals and subclinical atherosclerosis in carotid, femoral, and coronary vascular territories: the aragon workers health study

M Grau-Perez, MJ Caballero-Mateos… - … , and vascular biology, 2022 - Am Heart Assoc
Objective: Studies evaluating the association of metals with subclinical atherosclerosis are
mostly limited to carotid arteries. We assessed individual and joint associations of …