[HTML][HTML] Three-dimensional in vitro culture models in oncology research
Cancer is a multifactorial disease that is responsible for 10 million deaths per year. The intra-
and inter-heterogeneity of malignant tumors make it difficult to develop single targeted …
and inter-heterogeneity of malignant tumors make it difficult to develop single targeted …
[HTML][HTML] Decellularization in tissue engineering and regenerative medicine: evaluation, modification, and application methods
A Neishabouri, A Soltani Khaboushan… - … in bioengineering and …, 2022 - frontiersin.org
Reproduction of different tissues using scaffolds and materials is a major element in
regenerative medicine. The regeneration of whole organs with decellularized extracellular …
regenerative medicine. The regeneration of whole organs with decellularized extracellular …
[HTML][HTML] Diverse functions of macrophages in different tumor microenvironments
Tumor-associated macrophages are a major constituent of malignant tumors and are known
to stimulate key steps in tumor progression. In our review in this journal in 2006, we …
to stimulate key steps in tumor progression. In our review in this journal in 2006, we …
[HTML][HTML] Bearing my heart: the role of extracellular matrix on cardiac development, homeostasis, and injury response
AC Silva, C Pereira, ACRG Fonseca… - Frontiers in Cell and …, 2021 - frontiersin.org
The extracellular matrix (ECM) is an essential component of the heart that imparts
fundamental cellular processes during organ development and homeostasis. Most …
fundamental cellular processes during organ development and homeostasis. Most …
[HTML][HTML] The role of tumor microenvironment in chemoresistance: to survive, keep your enemies closer
DA Senthebane, A Rowe, NE Thomford… - International journal of …, 2017 - mdpi.com
Chemoresistance is a leading cause of morbidity and mortality in cancer and it continues to
be a challenge in cancer treatment. Chemoresistance is influenced by genetic and …
be a challenge in cancer treatment. Chemoresistance is influenced by genetic and …
[HTML][HTML] Preparation and use of decellularized extracellular matrix for tissue engineering
The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …
[HTML][HTML] The two faces of tumor-associated macrophages and their clinical significance in colorectal cancer
Macrophages are one of the immune populations frequently found in colorectal tumors and
high macrophage infiltration has been associated with both better and worst prognosis …
high macrophage infiltration has been associated with both better and worst prognosis …
[HTML][HTML] Recent trends in decellularized extracellular matrix bioinks for 3D printing: an updated review
The promise of regenerative medicine and tissue engineering is founded on the ability to
regenerate diseased or damaged tissues and organs into functional tissues and organs or …
regenerate diseased or damaged tissues and organs into functional tissues and organs or …
[HTML][HTML] Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis
Recent studies have shown that the tumor extracellular matrix (ECM) associates with
immunosuppression, and that targeting the ECM can improve immune infiltration and …
immunosuppression, and that targeting the ECM can improve immune infiltration and …
Reshaping the tumor stroma for treatment of pancreatic cancer
C Vennin, KJ Murphy, JP Morton, TR Cox, M Pajic… - Gastroenterology, 2018 - Elsevier
Pancreatic cancer is accompanied by a fibrotic reaction that alters interactions between
tumor cells and the stroma to promote tumor progression. Consequently, strategies to target …
tumor cells and the stroma to promote tumor progression. Consequently, strategies to target …