The essential role of tick salivary glands and saliva in tick feeding and pathogen transmission

L Šimo, M Kazimirova, J Richardson… - Frontiers in cellular and …, 2017 - frontiersin.org
As long-term pool feeders, ticks have developed myriad strategies to remain discreetly but
solidly attached to their hosts for the duration of their blood meal. The critical biological …

Tick salivary compounds: their role in modulation of host defences and pathogen transmission

M Kazimírová, I Štibrániová - Frontiers in cellular and infection …, 2013 - frontiersin.org
Ticks require blood meal to complete development and reproduction. Multifunctional tick
salivary glands play a pivotal role in tick feeding and transmission of pathogens. Tick …

[HTML][HTML] The role of saliva in tick feeding

IMB Francischetti, A Sa-Nunes, BJ Mans… - … in bioscience: a …, 2009 - ncbi.nlm.nih.gov
When attempting to feed on their hosts, ticks face the problem of host hemostasis (the
vertebrate mechanisms that prevent blood loss), inflammation (that can produce itching or …

Argasid and ixodid systematics: implications for soft tick evolution and systematics, with a new argasid species list

BJ Mans, J Featherston, M Kvas, KA Pillay… - Ticks and tick-borne …, 2019 - Elsevier
The systematics of the genera and subgenera within the soft tick family Argasidae is not
adequately resolved. Different classification schemes, reflecting diverse schools of scientific …

Anti-tick vaccines

P Willadsen - Parasitology, 2004 - cambridge.org
There is now abundant evidence that vaccination with defined protein antigens is able to
induce significant immunity to tick infestation. In a limited number of cases, this immunity has …

Host immune responses to salivary components-a critical facet of tick-host interactions

A Ali, I Zeb, A Alouffi, H Zahid, MM Almutairi… - Frontiers in Cellular …, 2022 - frontiersin.org
Tick sialome is comprised of a rich cocktail of bioactive molecules that function as a tool to
disarm host immunity, assist blood-feeding, and play a vibrant role in pathogen …

Adaptation of ticks to a blood-feeding environment: evolution from a functional perspective

BJ Mans, AWH Neitz - Insect biochemistry and molecular biology, 2004 - Elsevier
Ticks had to adapt to an existing and complex vertebrate hemostatic system from being free-
living scavengers. A large array of anti-hemostatic mechanisms evolved during this process …

Tick–host–pathogen interactions in Lyme borreliosis

JWR Hovius, AP van Dam, E Fikrig - Trends in parasitology, 2007 - cell.com
Borrelia burgdorferi, the spirochetal agent of Lyme borreliosis, is predominantly transmitted
by Ixodes ticks. Spirochetes have developed many strategies to adapt to the different …

Salivary glands in ixodid ticks: control and mechanism of secretion

JR Sauer, RC Essenberg, AS Bowman - Journal of insect physiology, 2000 - Elsevier
The salivary glands are vital to the biological success of ixodid ticks and the major route for
pathogen transmission. Important functions include the absorption of water vapor from …

Comparative sialomics between hard and soft ticks: implications for the evolution of blood-feeding behavior

BJ Mans, JF Andersen, IMB Francischetti… - Insect biochemistry and …, 2008 - Elsevier
Ticks evolved various mechanisms to modulate their host's hemostatic and immune
defenses. Differences in the anti-hemostatic repertoires suggest that hard and soft ticks …