Vitamin K health benefits have been recently widely shown to extend beyond blood
homeostasis and implicated in chronic low-grade inflammatory diseases such as …

The earliest description of calcific aortic stenosis is attributed to the French physician Lazare
Rivière who, in 1663, reported the necropsy findings from a patient with palpitations …

Untreated, severe, symptomatic aortic stenosis is associated with a dismal prognosis. The
only treatment shown to improve survival is aortic valve replacement; however, before …

Within the last few years, knowledge about vitamins has increased dramatically. This new
edition of a bestseller presents comprehensive summaries that analyze the chemical …

Vitamin K2 serves an important role in cardiovascular health through regulation of calcium
homeostasis. Its effects on the cardiovascular system are mediated through activation of the …

Matrix γ-carboxyglutamate (Gla) protein (MGP) is an important local inhibitor of vascular
calcification, which can undergo two post-translational modifications: vitamin K-dependent γ …

Vitamin K-antagonists (VKA) are the most widely used anti-thrombotic drugs with substantial
efficacy in reducing risk of arterial and venous thrombosis. Several lines of evidence …

Vitamin K has important functions within the body, some of which are still being discovered.
Research has shown that vitamin K is an anticalcification, anticancer, bone-forming and …

Vascular calcification, a cause of cardiovascular morbidity and mortality, is an actively
regulated process involving vitamin K dependent proteins (VKDPs) among others. Vitamin K …

Vitamin K-dependent (VKD) proteins undergo an unusual post-translational modification,
which is the conversion of specific Glu residues to carboxylated Glu (Gla). Gla generation is …