During gaseous exchange the lungs are exposed to a vast variety of pathogens, allergens,
and innocuous particles. A feature of the lung immune response to lung-tropic aerosol …

Rising rates of allergic disease accompany the healthier benefits of a contemporary
westernized lifestyle, such as low infant mortality. It is likely that these twinned phenomena …

Using a model of lethal oral infection with Toxoplasma gondii, we examined the fate of both
induced and natural regulatory T (Treg) cells in the face of strong inflammatory responses …

В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

The commensal flora can promote both immunity to pathogens and mucosal inflammation.
How commensal-driven inflammation is regulated in the context of infection remains poorly …

Although interferon γ (IFN-γ) secretion is essential for control of most intracellular pathogens,
host survival often also depends on the expression of interleukin 10 (IL-10), a cytokine …

Acute Trypanosoma cruzi infections can be asymptomatic, but chronically infected
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …

Toxoplasma gondii is one of the most successful protozoan parasites owing to its ability to
manipulate the immune system and establish a chronic infection. There are many T. gondii …

Toxoplasma gondii is an exceptionally successful parasite that infects a very broad host
range, including humans, across the globe. The outcome of infection differs remarkably …

Type I inflammatory cytokines are essential for immunity to many microbial pathogens,
including Toxoplasma gondii. Dendritic cells (DC) are key to initiating type 1 immunity, but …