Radiotherapy is one of the major therapeutic strategies for cancer treatment. In the past
decade, there has been growing interest in using high Z (atomic number) elements …

High-grade gliomas are usually of poor prognosis, and conventional radiotherapy, even
combined with chemotherapy, still fails to improve the survival of patients. Here, we propose …

Recently, nanoparticles have been considered as a method of providing radiation dose
enhancement in tumors. In order to quantify this affect, a dose enhancement factor (DEF) is …

Radiotherapy displays curative potential for cervical cancer management, but
radioresistance occurs during long-term therapy. To overcome this limitation, tumor-targeted …

Cisplatin is a widely used anticancer drug. It is documented that it elicits major side effects
like nephrotoxicity and hepatotoxicity due to oxidative stress forcing the patients to limit its …

A high efficiency and low toxicity radiosensitizer, OsN (PhenOH) Cl 3, was designed and
synthesized through substituent regulation. To the best of our knowledge, this is the first …

Concomitant treatment of radiotherapy and chemotherapy is widely used in cancer therapy.
The search for highly efficient radiochemotherapy drugs for tumor targeting therapy under …

We have evaluated the efficacy of intracerebral (ic) convection-enhanced delivery (CED) of
cisplatin in combination with photon irradiation for the treatment of F98 glioma-bearing rats …

Cisplatin is one of the most widely used anticancer drugs in the treatment of various types of
solid human cancers, as well as germ cell tumors, sarcomas, and lymphomas. Strong …

Purpose: The goal of the present study was to evaluate the efficacy of intracerebral (ic)
administration of carboplatin by means of convection-enhanced delivery (CED) in …