The nucleotide-binding domain leucine-rich repeat-receptor, pyrin domain-containing-3
(NLRP3) inflammasome contributes to the inflammatory response by activating caspase-1 …

Design, Analysis, and Pitfalls of Clinical Trials Using Ex S... : Transplantation Design, Analysis,
and Pitfalls of Clinical Trials Using Ex Situ Liver Machine Perfusion: The International Liver …

Background Transplantation of livers obtained from donors after circulatory death is
associated with an increased risk of nonanastomotic biliary strictures. Hypothermic …

Introduction Several clinical studies have demonstrated the safety, feasibility, and efficacy of
machine perfusion in liver transplantation, although its economic outcomes are still …

Objective The adoption of hearts from donation after circulatory death (DCD) is a promising
approach for the shortage of suitable organs in heart transplantation. However, DCD hearts …

Hepatic ischemia-reperfusion injury (IRI) is a multifactorial phenomenon which has been
associated with adverse clinical outcomes. IRI related tissue damage is characterized by …

A shortage of available organs for liver transplantation has led transplant surgeons and
researchers to seek for innovative approaches in hepatoprotection and improvement of …

Livers from donors after circulatory death (DCD) are a promising option to increase the
donor pool, but their use is associated with higher complication rate and inferior graft …

Although solid organ transplantation remains the definitive management for patients with
end-stage organ failure, this ultimate treatment has been limited by the number of …

Oxygen is the key molecule for aerobic metabolism, but no animal cells can produce it,
creating an extreme dependency on external supply. In contrast, microalgae are …