Critical care, like many healthcare areas, is under a dual assault from significantly
increasing demographic and economic pressures. Intensive care unit (ICU) patients are …

Pursuit of a closed-loop artificial pancreas that automatically controls the blood glucose of
individuals with type 1 diabetes has intensified during the past 6years. Here we discuss the …

In this two-part Bench to Clinic narrative, recent advances in both the preclinical and clinical
aspects of artificial pancreas (AP) development are described. In the preceding Bench …

Abstract Machine learning has become a popular tool for learning models of complex
dynamics from biomedical data. In Type 1 Diabetes (T1D) management, these models are …

OBJECTIVE To evaluate two widely used control algorithms for an artificial pancreas (AP)
under nonideal but comparable clinical conditions. RESEARCH DESIGN AND METHODS …

Background: In the past few years, the artificial pancreas—the commonly accepted term for
closed-loop control (CLC) of blood glucose in diabetes—has become a hot topic in research …

OBJECTIVE To evaluate the feasibility of a wearable artificial pancreas system, the Diabetes
Assistant (DiAs), which uses a smart phone as a closed-loop control platform. RESEARCH …

Automated insulin delivery (AID) systems, so-called closed-loop systems or artificial
pancreas, are based upon the concept of insulin supply driven by blood glucose levels and …

OBJECTIVE We estimate the effect size of hypoglycemia risk reduction on closed-loop
control (CLC) versus open-loop (OL) sensor-augmented insulin pump therapy in supervised …

Objective: Hybrid closed-loop (HCL) artificial pancreas (AP) systems are now moving from
research settings to widespread clinical use. In this study, the inControl algorithm developed …