Background: To recognize the action of pharmacologically approved anticancer drugs in
biological systems, information regarding its pharmacokinetics, such as its transport within …

Early diagnosis and effective treatment of cancer are challenging. To diagnose and treat
cancer effectively and to overcome these challenges, fundamental innovations in traditional …

Background Endometrial cancer (EC) is a common gynecologic malignancy worldwide. This
study investigated the regulatory effects of circular RNA (circRNA) hsa_circ_0002577 on the …

Background The purpose of this study was using bioinformatics tools to identify biomarkers
and molecular factors involved in the diagnosis of colorectal cancer, which are effective for …

Objective: This study aimed to find the key genes and miRNAs as potential biomarkers
related to the progression of colorectal cancer (CRC) from Crohn's disease (CD) …

Traditional cancer treatments have posed numerous obstacles, including toxicity, multiple
drug resistance, and financial cost. On the contrary, bioactive phytochemicals used in …

Aim: Our objective was to design and synthesize a new range of pyrazolopyrimidines while
maintaining the key pharmacophoric features of EGFR tyrosine kinase inhibitors. Materials & …

Purpose The aim of this study was evaluating the cytotoxic and radiosensitizing effects of
Ursolic Acid (UA) and Kamolonol Acetate (KA) on HCT116 cell line and finally investigating …

Preoperative radiochemotherapy is a promising therapeutic method for locally advanced
rectal cancer patients. However, the response of colorectal cancer (CRC) patients to …

ABSTRACT N6 methyladenosine (m6A), methylation at the sixth N atom of adenosine, is the
most common and abundant modification in mammalian mRNAs and non-coding RNAs …