Toxicology and pharmacology of synthetic organoselenium compounds: An update
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …
compounds and some naturally occurring organoselenium amino acids. The use of …
Aminolevulinate dehydratase (δ-ALA-D) as marker protein of intoxication with metals and other pro-oxidant situations
Abstract δ-ALA-D is a metalloenzyme that has 3 vicinal thiol/thiolate groups that coordinate
with Zn (ii). The proximity between the sulfhydryl groups renders δ-ALA-D extremely …
with Zn (ii). The proximity between the sulfhydryl groups renders δ-ALA-D extremely …
Involvement of oxidative stress in 4-vinylcyclohexene-induced toxicity in Drosophila melanogaster
AO Abolaji, JP Kamdem, TH Lugokenski… - Free Radical Biology …, 2014 - Elsevier
Vinylcyclohexene (VCH) is a dimer of 1, 3-butadiene produced as a by-product of pesticides,
plastic, rubber, flame retardants, and tire production. Although, several studies have …
plastic, rubber, flame retardants, and tire production. Although, several studies have …
QSAR and molecular docking modelling of anti-leishmanial activities of organic selenium and tellurium compounds
Leishmaniasis affects mainly rural areas and the poorest people in the world. A
computational study of the antileishmanial activity of organic selenium and tellurium …
computational study of the antileishmanial activity of organic selenium and tellurium …
Inorganic and methylmercury levels in plasma are differentially associated with age, gender, and oxidative stress markers in a population exposed to mercury through …
MFH Carneiro, D Grotto… - Journal of Toxicology and …, 2014 - Taylor & Francis
This study aimed to determine the concentrations of plasma methylmercury (Me-Hg) and
inorganic mercury (I-Hg) in a population exposed to Me-Hg. In addition, associations …
inorganic mercury (I-Hg) in a population exposed to Me-Hg. In addition, associations …
Thimerosal inhibits Drosophila melanogaster tyrosine hydroxylase (DmTyrH) leading to changes in dopamine levels and impaired motor behavior: implications for …
MC Bianchini, COA Gularte, PA Nogara, BN Krum… - Metallomics, 2019 - academic.oup.com
Thimerosal (THIM) is a well-established antifungal and antiseptic agent widely used as a
preservative in vaccines. Recent studies identified the neurotoxic effects of THIM, including …
preservative in vaccines. Recent studies identified the neurotoxic effects of THIM, including …
Diselenoamino acid derivatives as GPx mimics and as substrates of TrxR: in vitro and in silico studies
Excessive production of reactive species in living cells usually has pathological effects.
Consequently, the synthesis of compounds which can mimic the activity of antioxidant …
Consequently, the synthesis of compounds which can mimic the activity of antioxidant …
Cytotoxicity and genotoxicity evaluation of organochalcogens in human leucocytes: a comparative study between ebselen, diphenyl diselenide, and diphenyl …
D Caeran Bueno, DF Meinerz… - BioMed Research …, 2013 - Wiley Online Library
Organochalcogens, particularly ebselen, have been used in experimental and clinical trials
with borderline efficacy.(PhSe) 2 and (PhTe) 2 are the simplest of the diaryl dichalcogenides …
with borderline efficacy.(PhSe) 2 and (PhTe) 2 are the simplest of the diaryl dichalcogenides …
Effect of geraniol against arecoline induced toxicity in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9
B Shakya, S Shakya… - … Mechanisms and Methods, 2019 - Taylor & Francis
In the present study geraniol at the final concentration of 10, 20, 30, and 40 µM was mixed in
the diet along with 80 µM of arecoline and the third instar larvae of transgenic Drosophila …
the diet along with 80 µM of arecoline and the third instar larvae of transgenic Drosophila …
Evaluation of the pharmacological properties of salicylic acid-derivative organoselenium: 2-hydroxy-5-selenocyanatobenzoic acid as an anti-inflammatory and …
PM Chagas, SG Rosa, MHM Sari, CES Oliveira… - Pharmacology …, 2014 - Elsevier
The present study evaluated the antinociceptive and anti-inflammatory effects of per oral
(po) administration of salicylic acid-derivative organoselenium compounds in chemical …
(po) administration of salicylic acid-derivative organoselenium compounds in chemical …