Epicardial adipose tissue and cardiac lipotoxicity: A review

AG Mukherjee, K Renu, AV Gopalakrishnan, R Jayaraj… - Life Sciences, 2023 - Elsevier
Epicardial adipose tissue (EAT) has morphological and physiological contiguity with the
myocardium and coronary arteries, making it a visceral fat deposit with some unique …

A review of current and upcoming treatment modalities in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis

S Ganguli, P DeLeeuw… - … medicine: evidence and …, 2019 - Taylor & Francis
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in the West. Non-alcoholic steatohepatitis (NASH) is the progressive form of NAFLD and can …

Biology and therapeutic applications of peroxisome proliferator-activated receptors

MP Menendez-Gutierrez, T Roszer… - Current topics in …, 2012 - ingentaconnect.com
Peroxisome proliferator-activated receptors (PPARs) are ligand dependent transcription
factors. The three mammalian PPARs are key regulators of fatty acid and lipoprotein …

Current treatment options for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

MD Beaton - Canadian journal of gastroenterology and …, 2012 - Wiley Online Library
Nonalcoholic fatty liver disease is the leading cause of liver disease in western society. It is a
cause of end‐stage liver disease, with increased mortality secondary to cirrhosis and its …

Association between serum adipocytokine levels and microangiopathies in patients with type 2 diabetes mellitus

CH Jung, BY Kim, JO Mok, SK Kang… - Journal of diabetes …, 2014 - Wiley Online Library
Abstract Aims/Introduction It is thought that adipocytokines contribute to the increased risk of
vascular complications in type 2 diabetes. However, there is still limited information on the …

Effect of various treatments on leptin, adiponectin, ghrelin and neuropeptide Y in patients with type 2 diabetes mellitus

N Katsiki, DP Mikhailidis… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Several peptides are involved in the regulation of food intake and energy
expenditure, among which are leptin, adiponectin, ghrelin and neuropeptide Y (NPY). These …

[HTML][HTML] Narrative review of current and emerging pharmacological therapies for nonalcoholic steatohepatitis

J Satiya, HS Snyder, SP Singh… - Translational …, 2021 - ncbi.nlm.nih.gov
Nonalcoholic steatohepatitis (NASH) is the most common cause of chronic liver disease
today, and it has now emerged as the leading etiology of end-stage liver disease requiring …

Ezetimibe therapy for dyslipidemia: an update

N Katsiki, E Theocharidou… - Current …, 2013 - ingentaconnect.com
Ezetimibe, an inhibitor of intestinal cholesterol absorption, can decrease total cholesterol
(TC), low density lipoprotein cholesterol (LDL-C), triglycerides (TGs) and apolipoprotein …

Fibrate therapy and circulating adiponectin concentrations: a systematic review and meta-analysis of randomized placebo-controlled trials

A Sahebkar, GF Watts - Atherosclerosis, 2013 - Elsevier
Background Several lines of evidence have indicated the insulin-sensitizing, anti-diabetic
and anti-atherosclerotic properties of adiponectin, as well as the inverse association …

Novel treatment modalities for nonalcoholic steatohepatitis

SK Satapathy, AJ Sanyal - Trends in Endocrinology & Metabolism, 2010 - cell.com
Nonalcoholic steatohepatitis (NASH) is the most common cause of chronic liver disease in
the Western world. It can lead to cirrhosis and hepatocellular cancer, and is independently …