Serum antibodies directed against myelin oligodendrocyte glycoprotein (MOG) are found in
patients with acquired CNS demyelinating syndromes that are distinct from multiple sclerosis …

Neuromyelitis optica (NMO) is a chronic inflammatory autoimmune disease of the central
nervous system (CNS) characterized by acute optic neuritis (ON) and transverse myelitis …

Over the past few years, new-generation cell-based assays have demonstrated a robust
association of autoantibodies to full-length human myelin oligodendrocyte glycoprotein …

The term 'neuromyelitis optica spectrum disorders'(NMOSD) is used as an umbrella term that
refers to aquaporin-4 immunoglobulin G (AQP4-IgG)-positive neuromyelitis optica (NMO) …

Neuromyelitis optica (NMO) is an inflammatory CNS syndrome distinct from multiple
sclerosis (MS) that is associated with serum aquaporin-4 immunoglobulin G antibodies …

B cells are essential components of the adaptive immune system and have important roles
in the pathogenesis of several central nervous system (CNS) diseases. Besides producing …

Background A subset of patients with neuromyelitis optica spectrum disorders (NMOSD) has
been shown to be seropositive for myelin oligodendrocyte glycoprotein antibodies (MOG …

Background Antibodies to myelin oligodendrocyte glycoprotein (MOG-IgG) have been
suggested to play a role in a subset of patients with neuromyelitis optica and related …

Neuromyelitis optica spectrum disorders (NMOSD) are autoantibody mediated chronic
inflammatory diseases. Serum antibodies (Abs) against the aquaporin-4 water channel lead …

Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …