Recent advances on drug development and emerging therapeutic agents for Alzheimer's disease
T Athar, K Al Balushi, SA Khan - Molecular biology reports, 2021 - Springer
Alzheimer's disease (AD) is a neurodegenerative old age disease that is complex,
multifactorial, unalterable, and progressive in nature. The currently approved therapy …
multifactorial, unalterable, and progressive in nature. The currently approved therapy …
[HTML][HTML] Current understanding of Alzheimer's disease diagnosis and treatment
J Weller, A Budson - F1000Research, 2018 - ncbi.nlm.nih.gov
Alzheimer's disease is the most common cause of dementia worldwide, with the prevalence
continuing to grow in part because of the aging world population. This neurodegenerative …
continuing to grow in part because of the aging world population. This neurodegenerative …
Dementia prevention, intervention, and care
Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …
improve living and dying for individuals with dementia and their families, and in doing so …
Clinical neurology and epidemiology of the major neurodegenerative diseases
MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …
older adults. Most clinicians who care for the elderly are not trained to diagnose these …
Impact of patient and public involvement on enrolment and retention in clinical trials: systematic review and meta-analysis
Objective To investigate the impact of patient and public involvement (PPI) on rates of
enrolment and retention in clinical trials and explore how this varies with the context and …
enrolment and retention in clinical trials and explore how this varies with the context and …
Defeating Alzheimer's disease and other dementias: a priority for European science and society
Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …
Cognitive symptoms of Alzheimer's disease: clinical management and prevention
E Joe, JM Ringman - bmj, 2019 - bmj.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the
accumulation of amyloid β in the form of extracellular plaques and by intracellular …
accumulation of amyloid β in the form of extracellular plaques and by intracellular …
Alzheimer's disease: targeting the cholinergic system
TH Ferreira-Vieira, IM Guimaraes… - Current …, 2016 - ingentaconnect.com
Acetylcholine (ACh) has a crucial role in the peripheral and central nervous systems. The
enzyme choline acetyltransferase (ChAT) is responsible for synthesizing ACh from acetyl …
enzyme choline acetyltransferase (ChAT) is responsible for synthesizing ACh from acetyl …
Current and future treatments in Alzheimer's disease
A Atri - Seminars in neurology, 2019 - thieme-connect.com
The foundation of current Alzheimer's disease (AD) treatment involves pharmacological and
nonpharmacological management and care planning predicated on patient-centered …
nonpharmacological management and care planning predicated on patient-centered …
[HTML][HTML] Systematic review of systematic reviews of non-pharmacological interventions to treat behavioural disturbances in older patients with dementia. The …
I Abraha, JM Rimland, FM Trotta, G Dell'Aquila… - BMJ open, 2017 - bmjopen.bmj.com
Objective To provide an overview of non-pharmacological interventions for behavioural and
psychological symptoms in dementia (BPSD). Design Systematic overview of reviews. Data …
psychological symptoms in dementia (BPSD). Design Systematic overview of reviews. Data …