Bile acids and their derivatives as potential modifiers of drug release and pharmacokinetic profiles

N Pavlović, S Goločorbin-Kon, M Ðanić… - Frontiers in …, 2018 - frontiersin.org
Bile acids have received considerable interest in the drug delivery research due to their
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …

Bile acid‐based advanced drug delivery systems, bilosomes and micelles as novel carriers for therapeutics

M Nemati, A Fathi‐Azarbayjani… - Cell Biochemistry …, 2022 - Wiley Online Library
Diabetes mellitus affects almost half a billion patients worldwide and results from either
destruction of β‐cells responsible for insulin secretion or increased tissue resistance to …

Application of bile acids in drug formulation and delivery

M Stojančević, N Pavlović, S Goločorbin-Kon… - Frontiers in Life …, 2013 - Taylor & Francis
Bile acids are naturally produced in humans and are known to provide human health
benefits through their endocrinological, microfloral, metabolic and other åffects that are still …

{101}–{001} surface heterojunction-enhanced antibacterial activity of titanium dioxide nanocrystals under sunlight irradiation

N Liu, Y Chang, Y Feng, Y Cheng, X Sun… - … Applied Materials & …, 2017 - ACS Publications
The {101}–{001} surface heterojunction constructed on polyhedral titanium dioxide (TiO2)
nanocrystals has recently been proposed to be favorable for the efficient electron–hole …

Phytic acid enhances the oral absorption of isorhamnetin, quercetin, and kaempferol in total flavones of Hippophae rhamnoides L.

Y Xie, H Luo, J Duan, C Hong, P Ma, G Li, T Zhang… - Fitoterapia, 2014 - Elsevier
Abstract Aim Total flavones of Hippophae rhamnoides L.(TFH) have a clinical use in the
treatment of cardiac disease. The pharmacological effects of TFH are attributed to its major …

Protection mechanism of alginate microcapsules with different mechanical strength for Lactobacillus plantarum ST-III

M Zhao, F Qu, Z Wu, K Nishinari, GO Phillips, Y Fang - Food Hydrocolloids, 2017 - Elsevier
Alginate microcapsule is widely used to encapsulate and protect lactic acid bacteria (LAB).
This study aims to design microcapsules with different mechanical strength and clarify their …

Hyperammonemia enhances the function and expression of P‐glycoprotein and Mrp2 at the blood–brain barrier through NF‐κB

J Zhang, M Zhang, B Sun, Y Li, P Xu… - Journal of …, 2014 - Wiley Online Library
Ammonia is considered to be the main neurotoxin responsible for hepatic encephalopathy
resulting from liver failure. Liver failure has been reported to alter expression and activity of …

Sodium cholate-enhanced polymeric micelle system for tumor-targeting delivery of paclitaxel

X Zhang, Y Wu, M Zhang, J Mao, Y Wu… - International Journal …, 2017 - Taylor & Francis
Purpose Polymeric micelles are attractive nanocarriers for tumor-targeted delivery of
paclitaxel (PTX). High antitumor efficacy and low toxicity require that PTX mainly …

The role of the bile acid chenodeoxycholic acid in the targeted oral delivery of the anti-diabetic drug gliclazide, and its applications in type 1 diabetes

S Mathavan, N Chen-Tan, F Arfuso… - Artificial Cells …, 2016 - Taylor & Francis
Gliclazide (G) is used to treat type 2 diabetes (T2D), and also has anti-platelet, anti-radical,
and anti-inflammatory effects. G has poor water solubility and high inter-individual variations …

Mechanisms of P-gp inhibition and effects on membrane fluidity of a new rifampicin derivative, 1, 8-dibenzoyl-rifampicin

V Vilas-Boas, R Silva, C Nunes, S Reis, L Ferreira… - Toxicology Letters, 2013 - Elsevier
PURPOSE: To assess P-glycoprotein (P-gp)-modulation ability and the mechanisms of P-gp
inhibition mediated by a new synthetic rifampicin derivative, 1, 8-dibenzoyl-rifampicin …